Davison J M, Dunlop W, Ezimokhai M
Br J Obstet Gynaecol. 1980 Feb;87(2):106-9. doi: 10.1111/j.1471-0528.1980.tb04501.x.
Serial changes in 24-hour creatinine clearance were determined in 10 healthy women during late pregnancy and after the puerperium. A decrease occurred in all subjects during the six weeks preceding delivery, so that mean values for the last three weeks of pregnancy did not differ from the non-pregnant mean. Possible reasons for this phenomenon and its clinical implications are discussed.
对10名健康女性在妊娠晚期及产后的24小时肌酐清除率的系列变化进行了测定。在分娩前的六周内，所有受试者的肌酐清除率均出现下降，因此妊娠最后三周的平均值与非妊娠时的平均值无差异。讨论了这种现象的可能原因及其临床意义。
