乳糖不耐受儿童的再次调查：持续性乳糖不耐受与小肠形态、双糖酶活性及乳糖耐量试验之间缺乏相关性。
Reinvestigation of lactose intolerant children: lack of correlation between continuing lactose intolerance and small intestinal morphology, disaccharidase activity, and lactose tolerance tests.
作者信息
Harrison M, Walker-Smith J A
出版信息
Gut. 1977 Jan;18(1):48-52. doi: 10.1136/gut.18.1.48.
Abstract
Thirty children on a lactose-free diet aged from 2-38 months who had previously been diagnosed as having secondary lactose intolerance were reinvestigated on 32 occasions by an oral lactose tolerance test, small intestinal biopsy, and measurement of disaccharidase activity in order to detect the presence of continuing lactose intolerance before reintroduction of milk. No correlation was found between continuing lactose intolerance, as diagnosed by the development of watery stools containing excess reducing substances after an oral load of lactose, and maximum blood glucose rise during a lactose tolerance test, lactase levels, and small intestinal morphology.
摘要
对30名年龄在2至38个月、此前被诊断为继发性乳糖不耐受且食用无乳糖饮食的儿童，在重新引入牛奶之前，通过口服乳糖耐量试验、小肠活检和双糖酶活性测定等方法进行了32次复查，以检测持续乳糖不耐受的情况。口服乳糖负荷后出现含过量还原物质的水样便所诊断的持续乳糖不耐受，与乳糖耐量试验期间的最大血糖升高、乳糖酶水平和小肠形态之间未发现相关性。
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