Shliakhovenko V A, Negreĭ G Z
Vopr Onkol. 1980;26(3):40-4.
By methods of analytical electrophoresis nuclear chromatin proteins of normal and leukaemic hemopoietic rat cells were studied. There were revealed 1--2 extra bands in the histones extracted from chromatin of leukaemic cells. These proteins appear to be identical to histones of H10 type. The majority of nonhistone proteins of nuclear chromatin from normal and leukaemic hemopoietic cells show similar electrophoretic characteristics, whereas there were also found components typical for chromatin of only normal or leukaemic hemopoietic cells.
采用分析电泳方法,对正常和白血病大鼠造血细胞的核染色质蛋白进行了研究。从白血病细胞染色质中提取的组蛋白中发现了1 - 2条额外的条带。这些蛋白质似乎与H10型组蛋白相同。正常和白血病造血细胞核染色质的大多数非组蛋白显示出相似的电泳特征,然而也发现了仅正常或白血病造血细胞染色质特有的成分。