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通过体细胞杂交将二肽酶2基因定位到小家鼠18号染色体上。

Assignment of the gene for dipeptidase 2 to Mus musculus chromosome 18 by somatic cell hybridization.

作者信息

Leinwand L A, Ruddle F H

出版信息

Biochem Genet. 1978 Jun;16(5-6):477-84. doi: 10.1007/BF00484213.

Abstract

Evidence is presented for the assignment of the gene for dipeptidase 2 to Mus musculus chromosome 18 by synteny testing and karyotypic analysis of Chinese hamster x mouse somatic cell hybrid clones. DIP-2 and chromosome 18 were expressed concordantly in 24/24 clones examined (ten primary clones and 14 secondary clones). Synteny testing indicated that DIP-2 was not expressed concordantly with the expression of any marker enzymes.

摘要

通过对中国仓鼠与小鼠体细胞杂交克隆进行同线测试和核型分析,为将二肽酶2基因定位于小家鼠18号染色体提供了证据。在检测的24个克隆(10个初级克隆和14个次级克隆)中,DIP - 2和18号染色体一致表达。同线测试表明,DIP - 2与任何标记酶的表达均不一致。

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