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天疱疮中疾病活动度与抗体滴度的相关性

The correlation of disease activity and antibody titers in pemphigus.

作者信息

Fitzpatrick R E, Newcomer V D

出版信息

Arch Dermatol. 1980 Mar;116(3):285-90.

PMID:7369743
Abstract

Twenty cases of pemphigus extracted from the literature and 19 patients from UCLA with pemphigus were studied in detail regarding the possible correlation of pemphigus titer and disease activity. A statistically significant relationship between titer and disease activity, as well as change in titer and change in disease activity, was found. However, in spite of this relationship, serial titers were not found to be consistent enough to be used reliably as a guide to therapy or prognosis in pemphigus.

摘要

从文献中选取了20例天疱疮病例,并对加州大学洛杉矶分校的19例天疱疮患者进行了详细研究,以探讨天疱疮滴度与疾病活动度之间的可能相关性。研究发现,滴度与疾病活动度之间以及滴度变化与疾病活动度变化之间存在统计学上的显著关系。然而,尽管存在这种关系,但连续滴度的一致性不足以可靠地用作天疱疮治疗或预后的指导。

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