Pescatore D, Giberti C, Martorana G, Natta G, Giuliani L
Eur Urol. 1980;6(3):149-53. doi: 10.1159/000473314.
We have studied 38 patients with previously untreated, widespread prostatic cancer, who were submitted to therapy with cyproterone acetate and orchiectomy. 70% of patients with symptoms have shown subjective improvement. Moreover, it was possible to observe the regression, stabilization or progression of metastases in 32, 50 and 18% of the cases, respectively. We conclude that such therapy is effective in the initial treatment of metastatic prostate cancer and can be continued under radiographic control until the appearance of new metastases. At this point radiotherapy and alkylating agents may be effective.
我们研究了38例先前未经治疗的广泛性前列腺癌患者，这些患者接受了醋酸环丙孕酮和睾丸切除术治疗。70%有症状的患者显示出主观改善。此外，分别在32%、50%和18%的病例中观察到转移灶的消退、稳定或进展。我们得出结论，这种治疗方法对转移性前列腺癌的初始治疗有效，并且可以在影像学监测下持续进行，直到出现新的转移灶。此时，放射治疗和烷化剂可能有效。
