Schreiber V, Pribyl T, Jahodová J
Horm Metab Res. 1980 Mar;12(3):97-9. doi: 10.1055/s-2007-996213.
Serum polyphenol oxidase activity (ceruloplasmin) and the hypothalamic ascorbic acid concentration were determined in control rats and rats given estradiol for 2-6 months. A significant positive correlation (r = 0.5948, p less than 0.001) was found between adenohypophyseal weight and the ceruloplasmin level and a negative correlation between adenohypophyseal weight and the ascorbic acid concentration in the hypothalamus (r = -0.5728, p less than 0.01) and between the hypothalamus ascorbic acid concentration and the ceruloplasmin level (r = -0.7059, p less than 0.01). The ways in which an increase in serum polyphenol oxidase activity might modulate the adenohypophyseal reaction to estradiol are discussed.
在对照大鼠和给予雌二醇2至6个月的大鼠中测定了血清多酚氧化酶活性（铜蓝蛋白）和下丘脑抗坏血酸浓度。发现腺垂体重量与铜蓝蛋白水平之间存在显著正相关（r = 0.5948，p < 0.001），腺垂体重量与下丘脑抗坏血酸浓度之间存在负相关（r = -0.5728，p < 0.01），以及下丘脑抗坏血酸浓度与铜蓝蛋白水平之间存在负相关（r = -0.7059，p < 0.01）。讨论了血清多酚氧化酶活性增加可能调节腺垂体对雌二醇反应的方式。
