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弯曲杆菌肠炎中的黏膜侵袭

Mucosal invasion in campylobacter enteritis.

作者信息

Duffy M C, Benson J B, Rubin S J

出版信息

Am J Clin Pathol. 1980 May;73(5):706-8. doi: 10.1093/ajcp/73.5.706.

Abstract

Campylobacter fetus subspecies jejuni has recently been recognized as a significant cause of enteritis in humans. The organism has been previously postulated to cause illness by direct invasion of the mucosa of the gastrointestinal tract, but this has not been documented. Reported is a case of Campylobacter enteritis in which mucosal ulceration and crypt sbscesses were seen on rectal biopsy, suggesting that the pathogenesis of Campylobacter fetus enteritis involves direct mucosal invasion.

摘要

空肠弯曲菌胎儿亚种最近被认为是人类肠炎的一个重要病因。此前曾推测该病原体通过直接侵袭胃肠道黏膜导致疾病,但这一点尚未得到证实。本文报告了一例弯曲菌肠炎病例,直肠活检发现黏膜溃疡和隐窝脓肿,提示胎儿弯曲菌肠炎的发病机制涉及黏膜的直接侵袭。

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