Abelson M B, Yamamoto G K, Allansmith M R
Arch Ophthalmol. 1980 May;98(5):856-8. doi: 10.1001/archopht.1980.01020030850009.
Eight widely used commercially available ocular decongestants were compared on the basis of vasoconstrictive effectiveness. The ability of these preparations to counteract histamine-induced erythema and to block its recurrence when rechallenged after one hour was evaluated in six human subjects in seven sessions. All vasoconstrictors tested were effective. No preparation was statistically different from 0.02% naphazoline hydrochloride in vasoconstrictive effect. In fact, this intermediate concentration of naphazoline (0.02%) was found to be significantly better that the other nonprescription decongestant preparations tested as a group and not significantly different from a group of higher concentrations of naphazoline.
基于血管收缩效果，对八种广泛使用的市售眼部减充血剂进行了比较。在七个疗程中，对六名受试者评估了这些制剂对抗组胺诱导的红斑以及在一小时后再次激发时阻止其复发的能力。所有测试的血管收缩剂均有效。在血管收缩效果方面，没有一种制剂与0.02%盐酸萘甲唑啉在统计学上有差异。事实上，发现这种中等浓度的萘甲唑啉（0.02%）明显优于作为一组测试的其他非处方减充血剂制剂，并且与一组较高浓度的萘甲唑啉没有显著差异。
