Exner T, Barber S, Kronenberg H, Rickard K A
Br J Haematol. 1980 May;45(1):89-96. doi: 10.1111/j.1365-2141.1980.tb03814.x.
A lupus anticoagulant was detected in plasma from two pairs of siblings using the kaolin clotting time mixing test. Strong evidence for this inhibitor in one further sibling pair is presented. Although coagulation abnormalities are usually classified as either acquired or of genetic origin it is apparent that the lupus anticoagulant might often be an acquired coagulation defect requiring genetic predisposition.
通过高岭土凝血时间混合试验，在两对兄弟姐妹的血浆中检测到狼疮抗凝物。文中还给出了另外一对兄弟姐妹存在这种抑制剂的有力证据。尽管凝血异常通常分为获得性或遗传性，但很明显，狼疮抗凝物可能常常是一种需要遗传易感性的获得性凝血缺陷。
