de Klerk G, Vet R J, Rosengarten P C, Goudsmit R
Blood. 1980 Jun;55(6):955-9.
The commercially available hemagglutination inhibition (HAI) assay kit for erythropoietin (ESF) was compared with the fetal mouse liver cell (FMLC) bioassay. No correlation was obtained ESF levels determined by both methods in a variety of pathologic sera. The HAI kit showed a great batch variability. Significant immunoreactivity was found in those fractions of a normal human serum and a human urinary ESF preparation that were not active in the FMLC bioassay. A very poor recovery of immunoreactivity was found when the international reference preparation for erythropoietin (second IRPE) was added to a normal human serum.
将市售的促红细胞生成素（ESF）血凝抑制（HAI）检测试剂盒与胎鼠肝细胞（FMLC）生物测定法进行了比较。在多种病理血清中，两种方法测定的促红细胞生成素水平之间未发现相关性。HAI试剂盒显示出很大的批次差异。在正常人血清和人尿促红细胞生成素制剂的那些在FMLC生物测定中无活性的部分中发现了显著的免疫反应性。当将促红细胞生成素国际参考制剂（第二IRPE）添加到正常人血清中时，发现免疫反应性的回收率非常低。
