Sheorain V S, Nageswara Rao T, Subrahmanyam D
Enzyme. 1980;25(2):81-6. doi: 10.1159/000459223.
The mode of inhibition of Triton WR 1339 (oxyethylated t-octylphenol polymethylene polymer) on postheparin lipolytic activity and on lipoprotein lipase activity of heart, adipose tissue and liver has been studied in the mouse in vivo and in vitro. The low enzyme activity observed in the acetone powder extracts of the tissues of triton-treated mouse, which had no measurable triton levels together with the significant reversal of triton-inhibition in vitro by increasing concentrations of enzyme, suggested that the primary action of the detergent is on the enzyme per se.
已在小鼠体内和体外研究了吐温WR 1339（氧乙烯化叔辛基酚聚亚甲基聚合物）对肝素后脂解活性以及心脏、脂肪组织和肝脏脂蛋白脂肪酶活性的抑制方式。在经吐温处理的小鼠组织的丙酮粉提取物中观察到低酶活性，这些提取物中没有可测量的吐温水平，并且随着酶浓度的增加，吐温抑制在体外显著逆转，这表明去污剂的主要作用是直接作用于酶本身。
