Andersson S, Rosell S, Sjödin L, Folkers K
Scand J Gastroenterol. 1980;15(2):253-6. doi: 10.3109/00365528009181465.
In dogs with innervated fundic pouches an intravenous infusion of (Gln4)-neurotensin, 60 pmol X kg-1 X min-1, reduced the pentagastrin-stimulated acid secretion to 40% of the control secretory rate. After vagal denervation of the fundic pouches the same dose of (Gln4)-neurotensin did not significantly change the secretion. These findings suggest that (Gln4)-neurotensin does not act directly on parietal cells but inhibits acid secretion at a presynaptic level.
在具有神经支配的胃底小袋的犬中，静脉输注（Gln4）-神经降压素，剂量为60 pmol·kg⁻¹·min⁻¹，可使五肽胃泌素刺激的胃酸分泌降至对照分泌率的40%。在胃底小袋进行迷走神经切断后，相同剂量的（Gln4）-神经降压素并未显著改变分泌。这些发现表明，（Gln4）-神经降压素并不直接作用于壁细胞，而是在突触前水平抑制胃酸分泌。
