Minns R J, Steven F S
Ann Rheum Dis. 1980 Apr;39(2):164-7. doi: 10.1136/ard.39.2.164.
Human extensor tendons of the hand were pulled to rupture, and the torn ends, when observed in the scanning electron microscope, appeared to be knotted, possibly owing to the denaturation of the collagen. This confirmed by fluorimetry assays of both the ruptured ends and the middle unbroken sections of the same tendons. The use of a proteolytic enzyme, trypsin, to remove the denatured material and enhance the repair of organised collagen fibres from both ends is suggested if the ruptured ends have the denatured knotted appearance commonly observed clinically.
人类手部伸肌腱被牵拉至断裂，在扫描电子显微镜下观察时，撕裂端似乎呈打结状，这可能是由于胶原蛋白变性所致。对同一条肌腱的断裂端和中间未断裂部分进行荧光测定法验证了这一点。如果断裂端呈现出临床上常见的变性打结外观，建议使用蛋白水解酶胰蛋白酶去除变性物质，并促进两端有序胶原纤维的修复。
