Manton K G, Stallard E
Demography. 1980 May;17(2):189-206.
An analysis of the effects of diabetes and generalized atherosclerosis on death due to ischemic heart disease or stroke was conducted using multiple cause mortality statistics. Specifically, all U.S. deaths in 1969 were classified into two groups on the basis of whether diabetes or generalized atherosclerosis was mentioned anywhere on the death certificate. Then race and sex specific analyses were made of ischemic heart disease deaths (or alternately of stroke deaths) using modified life table techniques for each group (one with the specified chronic disease and one without). Comparisons were made of mortality due to the acute circulatory events (ischemic heart disease or stroke) in the two groups to determine the implications of the chronic disease for the progression of the circulatory disease events. It was found, according to expectations, that diabetes and generalized atherosclerosis play very different roles in deaths due to stroke and ischemic heart disease.
利用多病因死亡率统计数据,对糖尿病和全身性动脉粥样硬化对缺血性心脏病或中风所致死亡的影响进行了分析。具体而言,根据1969年美国死亡证明上是否提及糖尿病或全身性动脉粥样硬化,将所有死亡病例分为两组。然后,使用修正寿命表技术,对每组(一组患有特定慢性病,另一组没有)的缺血性心脏病死亡病例(或中风死亡病例)按种族和性别进行分析。比较两组急性循环系统疾病(缺血性心脏病或中风)的死亡率,以确定慢性病对循环系统疾病进展的影响。不出所料,研究发现糖尿病和全身性动脉粥样硬化在中风和缺血性心脏病所致死亡中发挥着截然不同的作用。