Manton K G, Patrick C H, Stallard E
Int J Epidemiol. 1980 Jun;9(2):111-20. doi: 10.1093/ije/9.2.111.
In this paper we examine the effects on life expectancy of elimination of 4 major causes of death. Methodologically, we compare the results of cause elimination under assumptions of pattern of failure elimination and assumptions of underlying cause elimination in a modified multiple-decrement life table framework for the segment of the population impacted. The 4 diseases selected for analysis are cancer, ischaemic heart disease, stroke, and diabetes, major killers among the elderly population. The degree to which life expectancy changes occur within the population from elimination of a given cause if a function of 3 factors: 1) distribution of age at death by cause for persons who die of that cause, 2) the gain in person years lived for those 'saved' from dying from that cause which has been eliminated, and 3) the proportion of all deaths which are due to the specific cause which is eliminated. Mortality data from the 1969 U.S. multiple cause mortality tapes from NCHS are analysed to determine the impact of life expectancy for males and females of both races when one of these 4 specific causes of death is eliminated.
在本文中,我们研究消除4种主要死因对预期寿命的影响。在方法上,我们在一个经过修改的多减量生命表框架内,针对受影响人群,比较在消除失效模式假设和潜在病因消除假设下的病因消除结果。选择用于分析的4种疾病为癌症、缺血性心脏病、中风和糖尿病,这些都是老年人口中的主要杀手。如果消除某一特定病因,预期寿命在人群中发生变化的程度取决于3个因素:1)死于该病因的人群按病因划分的死亡年龄分布;2)因消除该病因而“获救”的人群所获得的生存人年数;3)因消除该特定病因导致的所有死亡的比例。分析了美国国家卫生统计中心(NCHS)1969年多病因死亡率磁带中的死亡率数据,以确定消除这4种特定死因之一时,对两个种族男性和女性预期寿命的影响。