Effects of electrical stimulation on the enkephalins in guinea-pig small intestine.
作者信息
Corbett A D, Sosa R P, McKnight A T, Kosterlitz H W
出版信息
Eur J Pharmacol. 1980 Jul 11;65(1):113-7. doi: 10.1016/0014-2999(80)90219-8.
PMID:7398771
Abstract
When myenteric plexus-longitudinal muscle preparations of the guinea-pig small intestine are stimulated electrically in the presence of cycloheximide there is a decrease in the content of enkephalins which is taken to be due to their release. With supramaximal stimuli, the release per pulse is similar at 1 and 10 Hz but it is lower with submaximal than with maximal stimuli. Met-enkephalin is more readily released than Leu-enkephalin.
摘要
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