Corbett A D, Sosa R P, McKnight A T, Kosterlitz H W
Eur J Pharmacol. 1980 Jul 11;65(1):113-7. doi: 10.1016/0014-2999(80)90219-8.
When myenteric plexus-longitudinal muscle preparations of the guinea-pig small intestine are stimulated electrically in the presence of cycloheximide there is a decrease in the content of enkephalins which is taken to be due to their release. With supramaximal stimuli, the release per pulse is similar at 1 and 10 Hz but it is lower with submaximal than with maximal stimuli. Met-enkephalin is more readily released than Leu-enkephalin.
