Ferguson R, Basu M K, Asquith P, Cooke W T
Br Med J. 1976 Jan 3;1(6000):11-13. doi: 10.1136/bmj.1.6000.11.
Jejunal biopsies in 33 patients with troublesome recurrent aphthous ulceration seen over one year showed eight with flat mucosa compatible with coeliac disease. All remitted completely on a gluten-free diet, both clinically and haematologically, and the aphthous ulceration did not recur. Gluten sensitivity is aetiologically important in patients with recurrent aphthous ulceration and flat mucosa, and patients with recurrent ulceration should undergo jejunal biopsy.
在一年多时间里观察到的33例复发性阿弗他溃疡患者的空肠活检显示，有8例黏膜扁平，符合乳糜泻。所有患者在采用无麸质饮食后临床和血液学指标均完全缓解，阿弗他溃疡也未复发。麸质敏感性在复发性阿弗他溃疡且黏膜扁平的患者病因学中具有重要意义，复发性溃疡患者应接受空肠活检。
