Pribyl T, Jahodová J, Schreiber V
Horm Res. 1980;12(5):296-303.
The administration of silver nitrate to rats in their food (10 mg/rat/day) led to the rapid disappearance of serum polyphenol oxidase activity. After 60 days silver nitrate treatment produced a decrease of adenohypophyseal weight. If given over a period of 40--60 days it also partially inhibited the adenohypophyseal response to oestradiol (a weight decrease and raised thyroxine binding by adenohypophyseal proteins in vitro). The mechanism by which silver nitrate diminishes basal and oestrogen-increased adenohypophyseal weight remains unknown.
给大鼠喂食硝酸银（10毫克/大鼠/天）会导致血清多酚氧化酶活性迅速消失。硝酸银处理60天后，腺垂体重量减轻。如果连续40 - 60天给药，它还会部分抑制腺垂体对雌二醇的反应（腺垂体重量减轻，体外腺垂体蛋白质对甲状腺素的结合增加）。硝酸银减轻基础状态下和雌激素增加状态下腺垂体重量的机制尚不清楚。
