Berrens L, de Ridder G, de Boer F
Scand J Respir Dis. 1977 Aug;58(4):205-14.
A group of patients with serum precipitins against M. faeni culture filtrate antigens and with clinically proven farmer's lung disease was examined. A group of precipitin-negative farmers with comparable antigen exposure and with unrelated forms of pulmonary disease served as control. Immunoglobulins G and A were elevated at first consultation in the majority of the acute cases of farmer's lung. Immunological parameters normalized during corticosteroid medication and antigen avoidance. Autologous complement (C) consumption by M. Faeni antigens proved valuable for diagnostic purposes. Despite normalizing immunological factors and subsiding symptomatology, C-consuming antibody levels remained constant.
对一组血清中含有针对费氏放线菌培养滤液抗原的沉淀素且经临床确诊患有农民肺疾病的患者进行了检查。一组有类似抗原暴露但沉淀素阴性且患有非相关性肺部疾病的农民作为对照。在大多数农民肺急性病例的首次会诊时，免疫球蛋白G和A升高。在使用皮质类固醇药物治疗并避免接触抗原期间，免疫参数恢复正常。费氏放线菌抗原引起的自体补体（C）消耗被证明对诊断有价值。尽管免疫因子恢复正常且症状减轻，但补体消耗性抗体水平仍保持不变。
