Bronson R T
J Neurol Sci. 1980 Jul;47(1):105-9. doi: 10.1016/0022-510x(80)90029-5.
In 40 owl monkeys with hemolytic anemia of unknown etiology, 37 had a myopathy characterized by focal or diffuse necrosis of sarcoplasm which was eosinophilic and floccular. Phagocytosis of necrotic fibers and regenerative changes were also observed. The severity of lesions roughly paralleled the severity of anemia and of centrilobular hepatic necrosis assumed to be caused by hypoxia. That the myopathy was not caused by anemia per se was suggested by the finding of mild myopathy in 10 of 24 monkeys known never to have been severely anemic. Although anemic owl monkeys are known not to be deficient in either vitamin E or selenium, parenteral vitamin E is partially protective against hemolysis in this species. The myopathy, which resembled that caused by vitamin E or selenium deficiency in other species, is probably the result of a metabolic abnormality involving vitamin E in an unknown way.
在40只病因不明的溶血性贫血夜猴中，37只患有肌病，其特征为肌浆呈嗜酸性和絮状的局灶性或弥漫性坏死。还观察到坏死纤维的吞噬作用和再生变化。病变的严重程度大致与贫血的严重程度以及假定由缺氧引起的小叶中心性肝坏死的严重程度平行。在24只已知从未严重贫血的猴子中有10只出现轻度肌病，这表明肌病并非由贫血本身引起。虽然已知贫血的夜猴既不缺乏维生素E也不缺乏硒，但肠胃外补充维生素E对该物种的溶血有部分保护作用。这种肌病类似于其他物种中由维生素E或硒缺乏引起的肌病，可能是以一种未知方式涉及维生素E的代谢异常的结果。
