无龋和患龋现役军人中抗变形链球菌及葡糖基转移酶抗体的研究

Antibodies against Streptococcus mutans and glucosyltransferases in caries-free and caries-active military recruits.

Hus in 't Veld J, Bannet D, Van Palenstein Helderman W, Camargo P S, Backer-Dirks O

Adv Exp Med Biol. 1978;107:369-81. doi: 10.1007/978-1-4684-3369-2_42.

Abstract

Plaque samples from caries-active recruits showed a higher incidence of S. mutans than plaque samples from caries-free recruits. The persistance of the S. mutans serotypes in the individual plaque samples attested to the consistency of S. mutans in human dental plaque. 2) S. mutans serotype d is predominantly present in approximal plaque of caries-active subjects. 3) Serum antibody titers against S. mutans are higher in caries-active individuals. 4) Sera from caries-free or caries-active individuals inhibit the insoluble glucan synthesis by the cellbound GTF to the same extent. 5) It is unlikely that antibodies against S. mutans in parotid saliva or serum play a major role in the protection against dental caries in Dutch military recruits.

摘要

患龋新兵的菌斑样本中变形链球菌的发生率高于无龋新兵的菌斑样本。变形链球菌血清型在个体菌斑样本中的持续存在证明了变形链球菌在人类牙菌斑中的一致性。2) 变形链球菌血清型d主要存在于患龋个体的邻面菌斑中。3) 患龋个体中针对变形链球菌的血清抗体滴度较高。4) 无龋或患龋个体的血清对细胞结合型葡糖基转移酶介导的不溶性葡聚糖合成的抑制程度相同。5) 在荷兰新兵中，腮腺唾液或血清中针对变形链球菌的抗体在预防龋齿方面不太可能起主要作用。