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胚胎小鼠泌尿生殖窦间充质诱导胚胎膀胱上皮细胞核雄激素结合位点的产生。

Induction of nuclear androgen-binding sites in epithelium of the embryonic urinary bladder by mesenchyme of the urogenital sinus of embryonic mice.

作者信息

Cunha G R, Reese B A, Sekkingstad M

出版信息

Endocrinology. 1980 Dec;107(6):1767-70. doi: 10.1210/endo-107-6-1767.

DOI:10.1210/endo-107-6-1767
PMID:7428691
Abstract

Mesenchyme of the embryonic urogenital sinus induces epithelium of the embryonic urinary bladder to form prostatic acini. The induced glandular epithelium exhibits nuclear androgen-binding sites, as demonstrated autoradiographically. This suggests that the expression of androgen receptor activity in an epithelium is dependent upon the mesenchyme with which it is associated during development.

摘要

胚胎泌尿生殖窦的间充质诱导胚胎膀胱上皮形成前列腺腺泡。经放射自显影证实，诱导的腺上皮表现出核雄激素结合位点。这表明上皮细胞中雄激素受体活性的表达取决于其在发育过程中与之相关的间充质。

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1
Induction of nuclear androgen-binding sites in epithelium of the embryonic urinary bladder by mesenchyme of the urogenital sinus of embryonic mice.胚胎小鼠泌尿生殖窦间充质诱导胚胎膀胱上皮细胞核雄激素结合位点的产生。
Endocrinology. 1980 Dec;107(6):1767-70. doi: 10.1210/endo-107-6-1767.
2
Androgen-induced biochemical responses in epithelium lacking androgen receptors: characterization of androgen receptors in the mesenchymal derivative of urogenital sinus.雄激素诱导的缺乏雄激素受体的上皮细胞中的生化反应：泌尿生殖窦间充质衍生物中雄激素受体的特征
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Glandular epithelial induction by embryonic mesenchyme in adult bladder epithelium of BALB/c mice.BALB/c小鼠成年膀胱上皮中胚胎间充质对腺上皮的诱导作用。
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The possible influence of temporal factors in androgenic responsiveness of urogenital tissue recombinants from wild-type and androgen-insensitive (Tfm) mice.时间因素对野生型和雄激素不敏感（Tfm）小鼠泌尿生殖组织重组体雄激素反应性的可能影响。
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[Androgen receptors in the epithelium during prostatic gland induction from the urogenital sinus epithelium in Tfm-mutant mice].
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J Embryol Exp Morphol. 1981 Jun;63:207-23.

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