老年患者的去甲替林治疗：单剂量药代动力学研究后的剂量预测 - Suppr

Suppr

超能文献

Nortriptyline therapy in elderly patients: dosage prediction after single dose pharmacokinetic study.

作者信息

Dawling S, Crome P, Braithwaite R A, Lewis R R

出版信息

Eur J Clin Pharmacol. 1980 Aug;18(2):147-50. doi: 10.1007/BF00561582.

DOI:10.1007/BF00561582

PMID:7428795

Abstract

摘要

相似文献

Nortriptyline therapy in elderly patients: dosage prediction after single dose pharmacokinetic study.老年患者的去甲替林治疗：单剂量药代动力学研究后的剂量预测

Eur J Clin Pharmacol. 1980 Aug;18(2):147-50. doi: 10.1007/BF00561582.

Pharmacokinetics of single oral doses of nortriptyline in depressed elderly hospital patients and young healthy volunteers.单剂量口服去甲替林在老年抑郁症住院患者和年轻健康志愿者中的药代动力学。

Clin Pharmacokinet. 1980 Jul-Aug;5(4):394-401. doi: 10.2165/00003088-198005040-00007.

Pharmacokinetics of nortriptyline in elderly depressed patients and prediction of optimal dosage regimes [proceedings].去甲替林在老年抑郁症患者中的药代动力学及最佳给药方案预测 [会议论文集]

Br J Clin Pharmacol. 1980 Mar;9(3):306P-307P. doi: 10.1111/j.1365-2125.1980.tb04863.x.

Dosage adjustment from simple nortriptyline spot level predictor tests in depressed patients.根据抑郁症患者简单的去甲替林血药浓度预测测试进行剂量调整。

Clin Pharmacokinet. 1979 Mar-Apr;4(2):129-36. doi: 10.2165/00003088-197904020-00005.

Therapeutic effect and side effects in patients with endogenous depression treated with oral nortriptyline once a day.每日一次口服去甲替林治疗内源性抑郁症患者的疗效及副作用。

Neuropsychobiology. 1980;6(1):42-7. doi: 10.1159/000117731.

A pharmacokinetic approach to the treatment of depression.一种治疗抑郁症的药代动力学方法。

Int Pharmacopsychiatry. 1971;6(3):147-69. doi: 10.1159/000468267.

Nortriptyline therapy in elderly patients: dosage prediction from plasma concentration at 24 hours after a single 50 mg dose.

Br J Psychiatry. 1981 Nov;139:413-6. doi: 10.1192/bjp.139.5.413.

Monitoring plasma concentration of nortriptyline. Methodological, pharmakokinetic and clinical aspects.

Dan Med Bull. 1985 Mar;32(1):29-53.

[Antidepressive treatment with nortriptyline].

Ann Med Psychol (Paris). 1975 Jul;2(2):393-8.

First pass hydroxylation of nortriptyline: concentrations of parent drug and major metabolites in plasma.去甲替林的首过羟基化作用：血浆中母体药物及主要代谢物的浓度

Eur J Clin Pharmacol. 1977 Mar 11;11(3):219-24. doi: 10.1007/BF00606414.

引用本文的文献

Optimizing Nortriptyline Dosing: A Comparison between Pharmacogenetics-Based, Phenotype-Based, and Standard Dosing.优化去甲替林剂量：基于药物遗传学、基于表型和标准剂量的比较

Clin Pharmacokinet. 2025 May 25. doi: 10.1007/s40262-025-01528-x.

Am J Geriatr Pharmacother. 2012 Apr;10(2):139-50. doi: 10.1016/j.amjopharm.2012.01.001. Epub 2012 Jan 27.

Pharmacokinetic optimisation of tricyclic antidepressant therapy.三环类抗抑郁药治疗的药代动力学优化

Clin Pharmacokinet. 1993 Apr;24(4):301-18. doi: 10.2165/00003088-199324040-00004.

Clinical pharmacokinetics of antidepressants in the elderly. Therapeutic implications.老年人抗抑郁药的临床药代动力学。治疗意义。

Clin Pharmacokinet. 1993 Feb;24(2):141-60. doi: 10.2165/00003088-199324020-00004.

The pharmacokinetics of nortriptyline in patients with chronic renal failure.慢性肾衰竭患者中去甲替林的药代动力学

Br J Clin Pharmacol. 1981 Jul;12(1):39-45. doi: 10.1111/j.1365-2125.1981.tb01852.x.

Individualized aminophylline therapy in patients with obstructive airway disease: oral dosage prediction from an intravenous test dose.阻塞性气道疾病患者的个体化氨茶碱治疗：根据静脉试验剂量预测口服剂量

Eur J Clin Pharmacol. 1982;23(2):111-21. doi: 10.1007/BF00545964.

Clin Pharmacokinet. 1980 Jul-Aug;5(4):394-401. doi: 10.2165/00003088-198005040-00007.

Amitriptyline dosage prediction in elderly patients from plasma concentration at 24 hours after a single 100mg dose.

Clin Pharmacokinet. 1984 May-Jun;9(3):261-6. doi: 10.2165/00003088-198409030-00007.

Two prospective dosing methods for nortriptyline.去甲替林的两种前瞻性给药方法。

Clin Pharmacokinet. 1984 Nov-Dec;9(6):555-63. doi: 10.2165/00003088-198409060-00005.

Kinetics of citalopram in elderly patients.老年患者中西酞普兰的药代动力学

Psychopharmacology (Berl). 1985;86(3):253-7. doi: 10.1007/BF00432209.

本文引用的文献

Relationship between plasma level and therapeutic effect of nortriptyline.去甲替林血药浓度与治疗效果的关系。

Br Med J. 1971 Aug 7;3(5770):331-4. doi: 10.1136/bmj.3.5770.331.

Correlation of subjective side effects with plasma concentrations of nortriptyline.主观副作用与去甲替林血浆浓度的相关性。

Br Med J. 1970 Oct 3;4(5726):18-21. doi: 10.1136/bmj.4.5726.18.

Multiple dose kinetics and drug dosage in patients with kidney disease.肾病患者的多剂量动力学与药物剂量

Acta Pharmacol Toxicol (Copenh). 1971;29 Suppl 3:211-24. doi: 10.1111/j.1600-0773.1971.tb03301.x.

Psychotropic drugs and the elderly patient.精神药物与老年患者

Med J Aust. 1972 May 27;1(22):1131-3.

Prediction of steady-state plasma levels of nortriptyline from single oral dose kinetics: a study in twins.

Eur J Clin Pharmacol. 1973 Jun;6(1):44-53. doi: 10.1007/BF00561800.

Pharmacokinetics of nortriptyline in man after single and multiple oral doses: the predictability of steady-state plasma concentrations from single-dose plasma-level data.单剂量和多剂量口服后去甲替林在人体内的药代动力学：根据单剂量血浆水平数据预测稳态血浆浓度

Eur J Clin Pharmacol. 1972 Mar;4(2):82-91. doi: 10.1007/BF00562502.

Plasma nortriptyline levels--relationship to clinical effects.血浆去甲替林水平——与临床疗效的关系

Clin Pharmacol Ther. 1974 Jul;16(1):215-29.

A study of the use of antidepressant medication in general practice.一项关于全科医疗中抗抑郁药物使用情况的研究。

Br J Psychiatry. 1974 Aug;125(0):186-92. doi: 10.1192/bjp.125.2.186.

Commentary: a physiological approach to hepatic drug clearance.述评：肝脏药物清除的生理学方法

Clin Pharmacol Ther. 1975 Oct;18(4):377-90. doi: 10.1002/cpt1975184377.

First-pass metabolism of nortriptyline in man.

Clin Pharmacol Ther. 1975 Sep;18(3):305-14. doi: 10.1002/cpt1975183305.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验