McCarthy D S, Sigurdson M
Thorax. 1980 Apr;35(4):298-302. doi: 10.1136/thx.35.4.298.
Lung volumes, maximum expiratory flow rates, and static volume-ressure curves were measured in 16 patients with clinically stable asthma. It was found that flow rates were reduced in such patients because of the combined effects of reduced elastic recoil (transpulmonary pressure) and intrinsic diseases of the airways. In nine patients treated with an aerosol of isoprenaline, flow rates improved as a result of reduction in airways resistance as the static recoil pressure of the lungs fell further in those patients. The possibility is suggested that muscle tone in peripheral airways or alveolar ducts contributed to the elastic recoil measurements.
对16例临床症状稳定的哮喘患者进行了肺容量、最大呼气流量以及静态容量-压力曲线的测量。结果发现，这些患者的气流速率降低是由于弹性回缩力（跨肺压）降低和气道自身疾病共同作用的结果。在9例接受异丙肾上腺素气雾剂治疗的患者中，随着肺部静态回缩压力进一步下降，气道阻力降低，气流速率有所改善。这提示外周气道或肺泡导管中的肌张力可能影响了弹性回缩力的测量结果。
