Kanamycin ototoxicity and pigmentation in the guinea pig.
作者信息
Comis S D, Leng G
出版信息
Hear Res. 1980 Oct;3(3):249-51. doi: 10.1016/0378-5955(80)90051-9.
PMID:7440428
Abstract
Cochleas from albino and pigmented guinea pigs were examined histologically following chronic administration of Kanamycin. In pigmented animals, damage was concentrated amongst hair cells towards the base, but in albinos, hair cell damage was diffusely spread. These observations support suggestions that melanin is implicated in Kanamycin ototoxicity.
摘要
Zotero 插件