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1
Evaluation of the erythrocyte-UFA (E-UFA) mobility test for the diagnosis of multiple sclerosis.红细胞-不饱和脂肪酸(E-UFA)流动性测试用于多发性硬化症诊断的评估。
J Neurol Neurosurg Psychiatry. 1980 Nov;43(11):995-8. doi: 10.1136/jnnp.43.11.995.
2
Erythrocyte-UFA (Eufa) mobility test for multiple sclerosis: implications for pathogenesis and handling of the disease.用于多发性硬化症的红细胞-不饱和脂肪酸(Eufa)流动性测试:对疾病发病机制和治疗的启示
J Neurol. 1977 Jan 13;214(2):113-27. doi: 10.1007/BF02430349.
3
Red cell electrophoretic mobility test for early diagnosis of multiple sclerosis.红细胞电泳迁移率试验用于多发性硬化症的早期诊断。
Neurol Res. 1980;2(1):69-83. doi: 10.1080/01616412.1980.11739572.
4
Use of plasma for immediate diagnosis of multiple sclerosis (plasma-erythrocyte unsaturated fatty acid test): comparison with the erythrocyte-unsaturated fatty acid (E-UFA) test.利用血浆进行多发性硬化症的即时诊断(血浆-红细胞不饱和脂肪酸检测):与红细胞不饱和脂肪酸(E-UFA)检测的比较
Neurol Res. 1986 Mar;8(1):57-60. doi: 10.1080/01616412.1986.11739732.
5
The analysis of the red cell unsaturated fatty acid test for multiple sclerosis using laser cytopherometry.利用激光细胞光度术对多发性硬化症进行红细胞不饱和脂肪酸检测分析。
Phys Med Biol. 1983 Oct;28(10):1145-51. doi: 10.1088/0031-9155/28/10/006.
6
Simplified red-cell electrophoretic mobility test for multiple sclerosis.用于多发性硬化症的简化红细胞电泳迁移率测试。
Lancet. 1979 May 26;1(8126):1138-9. doi: 10.1016/s0140-6736(79)91813-0.
7
Erythrocyte electrophoretic mobility test for multiple sclerosis.用于多发性硬化症的红细胞电泳迁移率测试
Lancet. 1979 Jan 20;1(8108):165-6. doi: 10.1016/s0140-6736(79)90567-1.
8
E-UFA test in multiple sclerosis.多发性硬化症中的必需不饱和脂肪酸检测
Boll Ist Sieroter Milan. 1978 Jan 31;56(6):583-8.
9
Evaluation of the red blood cell cytopherometric test for the diagnosis of multiple sclerosis.红细胞血细胞比容检测用于多发性硬化症诊断的评估。
Acta Neurol Scand. 1977 Aug;56(2):170-6. doi: 10.1111/j.1600-0404.1977.tb01421.x.
10
Erythrocyte unsaturated fatty acid test (E-UFA test): a biological test to detect optic neuritis as initial feature of multiple sclerosis.红细胞不饱和脂肪酸试验(E-UFA试验):一种用于检测视神经炎作为多发性硬化症初始特征的生物学试验。
J Neurol. 1979 Jul 11;221(1):53-8. doi: 10.1007/BF00313169.

引用本文的文献

1
Comparison of membrane structure, osmotic fragility, and morphology of multiple sclerosis and normal erythrocytes.多发性硬化症患者与正常红细胞的膜结构、渗透脆性及形态学比较。
Neurochem Res. 1982 Dec;7(12):1523-40. doi: 10.1007/BF00965095.

本文引用的文献

1
A biochemical approach to the problem of multiple sclerosis.一种针对多发性硬化症问题的生化方法。
Proc R Soc Med. 1966 Mar;59(3):269-76. doi: 10.1177/003591576605900332.
2
Linoleate metabolism in multiple sclerosis.多发性硬化症中的亚油酸代谢
J Neurol Neurosurg Psychiatry. 1971 Feb;34(1):25-9. doi: 10.1136/jnnp.34.1.25.
3
Fatty acid composition of phospholipids from platelets and erythrocytes in multiple sclerosis.多发性硬化症患者血小板和红细胞中磷脂的脂肪酸组成
J Neurol Neurosurg Psychiatry. 1970 Aug;33(4):506-10. doi: 10.1136/jnnp.33.4.506.
4
Brain lipid modifications induced by essential fatty acid deficiency in growing male and female rats.必需脂肪酸缺乏对生长中雄性和雌性大鼠脑脂质的影响
J Neurochem. 1970 Mar;17(3):347-55. doi: 10.1111/j.1471-4159.1970.tb02221.x.
5
Linoleate and fatty-acid patterns of serum lipids in multiple sclerosis and other diseases.多发性硬化症及其他疾病中血清脂质的亚油酸和脂肪酸模式
Br Med J. 1974 Jul 6;3(5922):18-21. doi: 10.1136/bmj.3.5922.18.
6
Double-blind trial of linoleate supplementation of the diet in multiple sclerosis.饮食中补充亚油酸对多发性硬化症的双盲试验。
Br Med J. 1973 Mar 31;1(5856):765-8. doi: 10.1136/bmj.1.5856.765.
7
Diet and the geographical distribution of multiple sclerosis.
Lancet. 1974 Nov 2;2(7888):1061-6. doi: 10.1016/s0140-6736(74)92163-1.
8
Relationship between plasma and lymphocyte linoleate in multiple sclerosis.多发性硬化症中血浆与淋巴细胞亚油酸酯的关系。
J Neurol Neurosurg Psychiatry. 1976 Aug;39(8):767-71. doi: 10.1136/jnnp.39.8.767.
9
Evaluation of the red blood cell cytopherometric test for the diagnosis of multiple sclerosis.红细胞血细胞比容检测用于多发性硬化症诊断的评估。
Acta Neurol Scand. 1977 Aug;56(2):170-6. doi: 10.1111/j.1600-0404.1977.tb01421.x.
10
Linoleic acid in multiple sclerosis: failure to show any therapeutic benefit.亚油酸在多发性硬化症中的应用:未显示出任何治疗益处。
Acta Neurol Scand. 1978 Jul;58(1):53-8. doi: 10.1111/j.1600-0404.1978.tb02859.x.

红细胞-不饱和脂肪酸(E-UFA)流动性测试用于多发性硬化症诊断的评估。

Evaluation of the erythrocyte-UFA (E-UFA) mobility test for the diagnosis of multiple sclerosis.

作者信息

Cuypers J, Reddemann H

出版信息

J Neurol Neurosurg Psychiatry. 1980 Nov;43(11):995-8. doi: 10.1136/jnnp.43.11.995.

DOI:10.1136/jnnp.43.11.995
PMID:7441283
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC490750/
Abstract

The absolute electrophoretic mobility of red blood cells was examined before and after the addition of linoleic acid. The determinations were performed with a Zeiss cytopherometer. The blood was taken from 22 patients with multiple sclerosis in different phases of their disease. A group of 17 patients with other neurological diseases and three apparently healthy subjects served as controls. Our results show that the mobility of red blood cells was either accelerated or inhibited in the presence of linoleic acid, both in the multiple sclerosis patients as well as in the control group. The increase or inhibition of the absolute mobility was small and randomly distributed. The value of this so-called E-UFA test (erythrocyte-unsaturated fatty acid) as a specific diagnostic test for multiple sclerosis is not confirmed by our results.

摘要

在添加亚油酸前后检测了红细胞的绝对电泳迁移率。测定使用蔡司血细胞电泳仪进行。血液取自22例处于疾病不同阶段的多发性硬化症患者。一组17例患有其他神经系统疾病的患者和三名明显健康的受试者作为对照。我们的结果表明,在亚油酸存在的情况下,多发性硬化症患者以及对照组中红细胞的迁移率均有加快或受到抑制。绝对迁移率的增加或抑制幅度较小且呈随机分布。我们的结果并未证实这种所谓的E-UFA试验(红细胞-不饱和脂肪酸)作为多发性硬化症特异性诊断试验的价值。