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Comparative study of the electroencephalographic and behavioral effects of l-alpha-acetylmethadol (LAAM), two of its metabolites and morphine and methadone in the rat.

作者信息

Lukas S E, Moreton J E, Khazan N

出版信息

J Pharmacol Exp Ther. 1980 Nov;215(2):382-9.

PMID:7441502
Abstract
摘要

相似文献

1
Comparative study of the electroencephalographic and behavioral effects of l-alpha-acetylmethadol (LAAM), two of its metabolites and morphine and methadone in the rat.大鼠中左旋α-乙酰美沙多(LAAM)、其两种代谢物、吗啡及美沙酮的脑电图和行为效应的比较研究
J Pharmacol Exp Ther. 1980 Nov;215(2):382-9.
2
Differential electroencephalographic and behavioral cross tolerance to morphine and methadone in the l-alpha-acetylmethadol (LAAM)-maintained rat.在左旋 - α - 乙酰美沙醇(LAAM)维持给药的大鼠中,脑电图和行为学上对吗啡和美沙酮的交叉耐受性差异
J Pharmacol Exp Ther. 1982 Mar;220(3):561-7.
3
Effects of chronic treatment with morphine, methadone, and LAAM on the response to phencyclidine in rats.吗啡、美沙酮和左旋-α-乙酰美沙酮长期治疗对大鼠苯环利定反应的影响。
NIDA Res Monogr. 1979;27:212-8.
4
l-alpha-Acetylmethadol, l-alpha-acetyl-N-normethadol and l-alpha-acetyl-N,N-dinormethadol: comparisons with morphine and methadone in suppression of the opioid withdrawal syndrome in the dog.左旋α-乙酰美沙多、左旋α-乙酰-N-去甲美沙多和左旋α-乙酰-N,N-二去甲美沙多:与吗啡和美沙酮在抑制犬类阿片戒断综合征方面的比较。
J Pharmacol Exp Ther. 1997 Nov;283(2):833-42.
5
Pharmacodynamic profiles of 1-alpha-acetylmethadol (LAAM) and its N-demethylated metabolites, nor-LAAM and dinor-LAAM, during self-administration in the dependent rat.1-α-乙酰美沙多(LAAM)及其N-去甲基代谢产物去甲-LAAM和双去甲-LAAM在依赖大鼠自我给药过程中的药效学特征。
J Pharmacol Exp Ther. 1979 Sep;210(3):453-7.
6
The effects of levo-alpha-acetylmethadol and its metabolites on schedule-controlled behavior in the pigeon.左旋 -α- 乙酰美沙多及其代谢产物对鸽子按程序控制行为的影响。
J Pharmacol Exp Ther. 1981 Feb;216(2):299-305.
7
Duration of antinociceptive action of morphine, methadone and alpha-l-acetylmethadol subcutaneously in rats.吗啡、美沙酮和α-1-乙酰美沙酮皮下注射对大鼠的抗伤害感受作用持续时间。
Res Commun Chem Pathol Pharmacol. 1975 Dec;12(4):613-20.
8
Discriminative stimulus effects of l-alpha-acetylmethadol (LAAM), buprenorphine and methadone in morphine-treated rhesus monkeys.左旋 - α - 乙酰美沙多(LAAM)、丁丙诺啡和美沙酮在吗啡治疗的恒河猴中的辨别性刺激效应。
J Pharmacol Exp Ther. 1997 Aug;282(2):574-84.
9
Head-shake distributions during self-maintained dependence on morphine, methadone, and l-alpha-acetylmethadol (LAAM) in the rat.大鼠对吗啡、美沙酮和左旋-α-乙酰美沙朵(LAAM)产生自我维持依赖性期间的摇头分布情况。
Psychopharmacology (Berl). 1977 Aug 31;54(1):105-7. doi: 10.1007/BF00426549.
10
Heroin discriminative stimulus effects of methadone, LAAM and other isomers of acetylmethadol in rats.美沙酮、左旋α-乙酰美沙朵及乙酰美沙朵其他异构体在大鼠体内的海洛因辨别刺激效应
Psychopharmacology (Berl). 2002 Oct;164(1):108-14. doi: 10.1007/s00213-002-1198-8. Epub 2002 Aug 9.

引用本文的文献

1
Pharmacological classification of centrally acting drugs using EEG in freely moving rats: an old tool to identify new atypical dopamine uptake inhibitors.使用自由活动大鼠的 EEG 对中枢作用药物进行药理学分类:识别新型非典型多巴胺摄取抑制剂的旧工具。
Neuropharmacology. 2019 Dec 15;161:107446. doi: 10.1016/j.neuropharm.2018.11.034. Epub 2018 Nov 24.
2
Acetylmethadol versus methadone: human mood and motility.乙酰美沙酮与美沙酮:对人类情绪和运动能力的影响
Psychopharmacology (Berl). 1985;86(4):458-63. doi: 10.1007/BF00427908.
3
Variability in simian motor and social behavior with alternating-day acetylmethadol.
交替日服用醋美沙朵时猕猴运动和社会行为的变异性
Psychopharmacology (Berl). 1985;85(3):353-60. doi: 10.1007/BF00428201.