用病毒包膜糖蛋白复合物分离出的弗氏小鼠白血病病毒可能的细胞表面受体。
Possible cell surface receptor for Friend murine leukemia virus isolated with viral envelope glycoprotein complexes.
作者信息
Robinson P J, Hunsmann G, Schneider J, Schirrmacher V
出版信息
J Virol. 1980 Oct;36(1):291-4. doi: 10.1128/JVI.36.1.291-294.1980.
Abstract
Water-soluble multimeric complexes of Friend leukemia virus envelope glycoprotein gp85 bind specifically to C57BL/6 mouse spleen leukocytes. Such complexes were used to isolate cell surface receptors for the virus, using an immunoprecipitation technique. The putative rceptor has a molecular weight of 14,000. Mouse H-2 histocompatibility antigens, which are receptors for Semliki Forest virus, are not receptors for Friend leukemia virus.
摘要
弗瑞德白血病病毒包膜糖蛋白gp85的水溶性多聚体复合物能特异性结合C57BL/6小鼠脾脏白细胞。利用免疫沉淀技术，此类复合物被用于分离该病毒的细胞表面受体。推测的受体分子量为14,000。作为辛德毕斯病毒受体的小鼠H-2组织相容性抗原并非弗瑞德白血病病毒的受体。
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