• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

盐诱导的聚（dA-dT）构象变化。

Salt-induced conformational changes of poly(dA-dT).

作者信息

Vorlícková M, Kypr J, Kleinwächter V, Palecek E

出版信息

Nucleic Acids Res. 1980 Sep 11;8(17):3965-73. doi: 10.1093/nar/8.17.3965.

DOI:10.1093/nar/8.17.3965
PMID:7443518
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC324207/
Abstract

Conformational changes of poly(dA-dT) . poly(dA-dT) induced by increasing ionic strength were studied using CD spectroscopy. It was found that a pronounced noncooperative inversion of the long-wavelength part of the CD spectrum of poly(dA-dT) . poly(dA-dT) occurred at high concentrations of CsF in solution. It was suggested that a great difference between the geometries of the purine and pyrimidine residues in the helix was characteristic of the structure of poly(dA-dT) . poly(dA-dT) in concentrated CsF solutions.

摘要

使用圆二色光谱法研究了离子强度增加引起的聚（dA-dT）·聚（dA-dT）的构象变化。发现在溶液中CsF高浓度时，聚（dA-dT）·聚（dA-dT）的圆二色光谱长波长部分发生了明显的非协同反转。有人提出，螺旋中嘌呤和嘧啶残基几何形状的巨大差异是聚（dA-dT）·聚（dA-dT）在浓CsF溶液中结构的特征。

相似文献

1
Salt-induced conformational changes of poly(dA-dT).盐诱导的聚（dA-dT）构象变化。
Nucleic Acids Res. 1980 Sep 11;8(17):3965-73. doi: 10.1093/nar/8.17.3965.
2
Conformational variability of poly(dA-dT).poly(dA-dT) and some other deoxyribonucleic acids includes a novel type of double helix.聚（dA-dT）·聚（dA-dT）及其他一些脱氧核糖核酸的构象变异性包括一种新型双螺旋结构。
J Biomol Struct Dyn. 1985 Aug;3(1):67-83. doi: 10.1080/07391102.1985.10508399.
3
Solution structure of poly(dA-dT).poly(dA-dT) in low and high salt: a 500 MHz 1H NMR study using one-dimensional NOE.聚（dA-dT）·聚（dA-dT）在低盐和高盐条件下的溶液结构：一项使用一维核Overhauser效应的500兆赫质子核磁共振研究。
J Biomol Struct Dyn. 1984 Jun;1(6):1423-55. doi: 10.1080/07391102.1984.10507529.
4
Conformational peculiarities of polynucleotides with a nonrandom base sequence according to the 1H----3H exchange rate in C8H groups of purinic residues.根据嘌呤残基C8H基团中1H→3H的交换率，具有非随机碱基序列的多核苷酸的构象特性。
J Biomol Struct Dyn. 1987 Dec;5(3):601-14. doi: 10.1080/07391102.1987.10506415.
5
Salt-induced conformational transition of poly[d(A-T)] X poly[d(A-T)].聚[d(A-T)]×聚[d(A-T)]的盐诱导构象转变
J Mol Biol. 1983 May 5;166(1):85-92. doi: 10.1016/s0022-2836(83)80052-7.
6
Raman spectroscopic elucidation of DNA backbone conformations for poly(dG-dT).poly(dA-dC) and poly(dA-dT).poly(dA-dT) in CsF solution.拉曼光谱法阐明CsF溶液中聚（dG-dT）·聚（dA-dC）和聚（dA-dT）·聚（dA-dT）的DNA主链构象
Biopolymers. 1985 Aug;24(8):1493-500. doi: 10.1002/bip.360240806.
7
A polycationic amine that induces unique conformational changes in poly(dA-dT) in low salt.一种在低盐条件下能诱导聚（dA-dT）发生独特构象变化的聚阳离子胺。
Nucleic Acids Res. 1984 Aug 10;12(15):6325-35. doi: 10.1093/nar/12.15.6325.
8
Conformational transitions of poly(dA-dC).poly(dG-dT) induced by high salt or in ethanolic solution.高盐或乙醇溶液诱导的聚（dA-dC）·聚（dG-dT）的构象转变
Nucleic Acids Res. 1982 Feb 11;10(3):1081-91. doi: 10.1093/nar/10.3.1081.
9
Conformational transitions of poly(dA-dT)poly(dA-dT) in ethanolic solutions.聚（dA-dT）聚（dA-dT）在乙醇溶液中的构象转变。
Nucleic Acids Res. 1982 Nov 11;10(21):6969-79. doi: 10.1093/nar/10.21.6969.
10
A Z-like form of poly(dA-dC).poly(dG-dT) in solution?溶液中聚（dA-dC）·聚（dG-dT）的Z型结构？
Nucleic Acids Res. 1982 Feb 11;10(3):1071-80. doi: 10.1093/nar/10.3.1071.

引用本文的文献

1
Conformational transitions of poly(dA-dT)poly(dA-dT) in ethanolic solutions.聚（dA-dT）聚（dA-dT）在乙醇溶液中的构象转变。
Nucleic Acids Res. 1982 Nov 11;10(21):6969-79. doi: 10.1093/nar/10.21.6969.
2
The influence of the purine 2-amino group on DNA conformation and stability. Synthesis and conformational analysis of d[T(2-aminoA)]3.嘌呤2-氨基对DNA构象和稳定性的影响。d[T(2-氨基A)]3的合成与构象分析。
Nucleic Acids Res. 1982 Jul 24;10(14):4351-61. doi: 10.1093/nar/10.14.4351.
3
Conformational transitions of poly(dA-dC).poly(dG-dT) induced by high salt or in ethanolic solution.高盐或乙醇溶液诱导的聚（dA-dC）·聚（dG-dT）的构象转变
Nucleic Acids Res. 1982 Feb 11;10(3):1081-91. doi: 10.1093/nar/10.3.1081.
4
A Z-like form of poly(dA-dC).poly(dG-dT) in solution?溶液中聚（dA-dC）·聚（dG-dT）的Z型结构？
Nucleic Acids Res. 1982 Feb 11;10(3):1071-80. doi: 10.1093/nar/10.3.1071.
5
Right-handed alternating DNA conformation: poly(dA-dT) adopts the same dinucleotide repeat with cesium, tetraalkylammonium, and 3 alpha, 5 beta, 17 beta-dipyrrolidinium steroid dimethiodide cations in aqueous solution.右手交替DNA构象：在水溶液中，聚（dA-dT）与铯、四烷基铵和3α，5β，17β-二吡咯烷鎓甾体二甲碘化物阳离子采用相同的二核苷酸重复序列。
Proc Natl Acad Sci U S A. 1981 Jul;78(7):4063-7. doi: 10.1073/pnas.78.7.4063.
6
Intercalative and nonintercalative binding of large cationic porphyrin ligands to polynucleotides.大阳离子卟啉配体与多核苷酸的插入和非插入结合
Nucleic Acids Res. 1983 Sep 10;11(17):6141-54. doi: 10.1093/nar/11.17.6141.
7
A polycationic amine that induces unique conformational changes in poly(dA-dT) in low salt.一种在低盐条件下能诱导聚（dA-dT）发生独特构象变化的聚阳离子胺。
Nucleic Acids Res. 1984 Aug 10;12(15):6325-35. doi: 10.1093/nar/12.15.6325.
8
Osmium tetroxide: a new probe for site-specific distortions in supercoiled DNAs.四氧化锇：超螺旋DNA中位点特异性扭曲的新型探针。
Nucleic Acids Res. 1984 Feb 10;12(3):1725-35. doi: 10.1093/nar/12.3.1725.
9
Right-handed and left-handed helices of poly(dA-dC) X (dG-dT).聚（dA-dC）×（dG-dT）的右手螺旋和左手螺旋
Nucleic Acids Res. 1985 Jun 25;13(12):4469-83. doi: 10.1093/nar/13.12.4469.
10
Kinetics of the proton-deuteron exchange at position H8 of adenine and guanine in DNA.DNA中腺嘌呤和鸟嘌呤H8位置的质子-氘核交换动力学。
Nucleic Acids Res. 1986 Dec 9;14(23):9491-508. doi: 10.1093/nar/14.23.9491.

本文引用的文献

1
Conformation and reactivity of DNA V. pH-dependent conformational changes of DNA in complexes with poly-L-histidine: Transitions from B- to A-form and to a condensed state.DNA的构象与反应性V. 与聚-L-组氨酸形成复合物时DNA的pH依赖性构象变化：从B型到A型以及到凝聚态的转变
FEBS Lett. 1973 Feb 15;30(1):35-39. doi: 10.1016/0014-5793(73)80613-1.
2
Left-handed DNA helices.左手DNA螺旋
Nature. 1980 Feb 21;283(5749):743-5. doi: 10.1038/283743a0.
3
Dynamic light-scattering studies of DNA. II. Effect of ionic strength on the structure and internal dynamics of viral phi 29 DNA.
Biopolymers. 1980 Jan;19(1):215-8. doi: 10.1002/bip.1980.360190115.
4
Conformational changes associated with f-1 histone-deoxyribonucleic acid complexes. Circular dichroism studies.与F-1组蛋白-脱氧核糖核酸复合物相关的构象变化。圆二色性研究。
Biochemistry. 1970 Jul 7;9(14):2814-22. doi: 10.1021/bi00816a010.
5
Difference between polylysine and polyarginine in changing DNA structure upon complex formation.
Biochem Biophys Res Commun. 1971 Aug 20;44(4):936-42. doi: 10.1016/0006-291x(71)90802-3.
6
Salt-induced co-operative conformational change of a synthetic DNA: equilibrium and kinetic studies with poly (dG-dC).盐诱导的合成DNA的协同构象变化：聚（dG-dC）的平衡和动力学研究
J Mol Biol. 1972 Jun 28;67(3):375-96. doi: 10.1016/0022-2836(72)90457-3.
7
Circular dichroism of DNA: temperature and salt dependence.DNA的圆二色性：温度和盐依赖性
Biopolymers. 1972;11(4):761-79. doi: 10.1002/bip.1972.360110404.
8
Circular dichroism spectra of oriented and unoriented deoxyribonucleic acid films--a preliminary study.定向和非定向脱氧核糖核酸薄膜的圆二色光谱——一项初步研究。
J Mol Biol. 1970 Sep 28;52(3):521-41. doi: 10.1016/0022-2836(70)90417-1.
9
Protonated polynucleotide structures. Sequence-dependent and protonation-sensitive metastable states in DNA premelting.质子化多核苷酸结构。DNA预熔解中依赖序列且对质子化敏感的亚稳态。
Eur J Biochem. 1973 Apr;34(2):232-40. doi: 10.1111/j.1432-1033.1973.tb02751.x.
10
Different conformations of double-stranded nucleic acid in solution as revealed by circular dichroism.圆二色光谱揭示溶液中双链核酸的不同构象。
Biopolymers. 1973;12(1):89-110. doi: 10.1002/bip.1973.360120109.