高盐或乙醇溶液诱导的聚（dA-dC）·聚（dG-dT）的构象转变
Conformational transitions of poly(dA-dC).poly(dG-dT) induced by high salt or in ethanolic solution.
作者信息
Zimmer C, Tymen S, Marck C, Guschlbauer W
出版信息
Nucleic Acids Res. 1982 Feb 11;10(3):1081-91. doi: 10.1093/nar/10.3.1081.
Abstract
Poly(dA-dC).poly(dG-dT) was studied by circular dichroism in the presence of high CsCl concentrations and in ethanolic solutions. This alternating purine-pyrimidine duplex may undergo two conformational transitions from a B-type to a novel structure and subsequently into an A-form. Cs+ ions or increasing ethanol concentrations induced a change of the B-type CD spectrum and an inversion of the long wavelength CD band. Lowering the temperature below 0 C or addition of small amounts of Ca++ ions were particularly potent in producing a large negative CD band. A modified B-type structure or a conversion into a left-handed Z-form is considered for this conformational transition.
摘要
在高浓度氯化铯存在的情况下以及在乙醇溶液中，通过圆二色性对聚（dA-dC）·聚（dG-dT）进行了研究。这种交替的嘌呤-嘧啶双链体可能经历从B型到一种新结构，随后再转变为A型的两种构象转变。铯离子或乙醇浓度的增加会导致B型圆二色光谱发生变化以及长波长圆二色带发生反转。将温度降低至0℃以下或添加少量钙离子在产生大的负圆二色带方面特别有效。这种构象转变被认为是形成了一种修饰的B型结构或转变为左手Z型。
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本文引用的文献
1
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2
Polymorphism of DNA double helices.DNA双螺旋的多态性
J Mol Biol. 1980 Oct 15;143(1):49-72. doi: 10.1016/0022-2836(80)90124-2.
3
Crystal structure analysis of a complete turn of B-DNA.B型DNA完整一圈的晶体结构分析。
Nature. 1980 Oct 23;287(5784):755-8. doi: 10.1038/287755a0.
4
High-salt d(CpGpCpG), a left-handed Z' DNA double helix.高盐条件下的d（CpGpCpG），一种左手Z'型DNA双螺旋结构。
Nature. 1980 Aug 7;286(5773):567-73. doi: 10.1038/286567a0.
5
Left-handed DNA helices.左手DNA螺旋
Nature. 1980 Feb 21;283(5749):743-5. doi: 10.1038/283743a0.
6
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7
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