Elner V M, Schaffner T, Taylor K, Glagov S
Science. 1981 Jan 2;211(4477):74-6. doi: 10.1126/science.7444450.
Retinal pigment cells were dislodged from normal monkey eyes and incubated in glass-slide chambers. All viable pigment cells adhered strongly to glass. They demonstrated surface receptors for the Fc portion of immunoglobulin G and for the third component of complement by selectively binding and phagocytizing antibody or complement-coated erythrocytes. These phagocytic cells with receptors were identified as retinal pigment cells by characteristic ultrastructural features. Thus, retinal pigment cells, which are generally believed to be derived from neural tissue, are not only scavengers of photoreceptor cell debris, but also have surface receptors and phagocytic functions that may be important in ocular defense.
视网膜色素细胞从正常猴眼中分离出来，置于载玻片小室中培养。所有存活的色素细胞都牢固地黏附在玻璃上。它们通过选择性结合并吞噬抗体或补体包被的红细胞，展示出针对免疫球蛋白G的Fc段和补体第三成分的表面受体。这些带有受体的吞噬细胞通过特征性超微结构特征被鉴定为视网膜色素细胞。因此，通常被认为源自神经组织的视网膜色素细胞，不仅是光感受器细胞碎片的清除者，还具有可能在眼部防御中起重要作用的表面受体和吞噬功能。
