Wyatt H L, Meerbaum S, Heng M K, Gueret P, Corday E
Am Heart J. 1980 Dec;100(6 Pt 1):821-8. doi: 10.1016/0002-8703(80)90062-9.
Cross-sectional echocardiography was utilized for quantification of volume in 19 formalin-fixed left ventricles in the presence or absence of ventricular symmetry, defined by the ratio of septal-lateral to anterior-posterior diameter. In 10 symmetric ventricles this ratio was 1.23 +/- 0.06 (mean +/- SEM), whereas in nine asymmetric ventricles the ratio was 1.80 +/- 0.07. Area, diameter, and length measurements were obtained from short- and long-axis cross-sectional images of the left ventricle and volume was calculated by five mathematical models previously described. To evaluate the reliability of each model, echocardiographic left ventricular volume was compared by linear regression and percent error analyses to directly measured fluid volume. In symmetric ventricles, excellent correlations (r = 0.996 to 0.967) and reasonable mean percent errors (6% to 31%) were observed for all models. In asymmetric ventricles, models utilizing short-axis area or two short-axis diameters retained high correlation coefficients (r = 0.985 to 0.956) and similar mean percent errors, but standard formulas previously used with M-mode echo and angiography showed lower correlations (r = 0.886 to 0.873) and higher mean percent errors (52% to 54%). Thus, in the presence of ventricular asymmetry, analysis of short-axis areas or diameters with cross-sectional echocardiography is well suited for quantification of left ventricular volumes.
利用横截面超声心动图对19个经福尔马林固定的左心室进行容积定量，这些左心室存在或不存在心室对称性，心室对称性由室间隔-侧壁与前后径的比值定义。在10个对称心室中，该比值为1.23±0.06（平均值±标准误），而在9个不对称心室中，该比值为1.80±0.07。从左心室的短轴和长轴横截面图像中获取面积、直径和长度测量值，并通过先前描述的五种数学模型计算容积。为了评估每个模型的可靠性，通过线性回归和百分比误差分析将超声心动图左心室容积与直接测量的液体容积进行比较。在对称心室中，所有模型均观察到极好的相关性（r = 0.996至0.967）和合理的平均百分比误差（6%至31%）。在不对称心室中，利用短轴面积或两个短轴直径的模型保持了较高的相关系数（r = 0.985至0.956）和相似的平均百分比误差，但先前用于M型超声心动图和血管造影的标准公式显示相关性较低（r = 0.886至0.873）和平均百分比误差较高（52%至54%）。因此，在存在心室不对称的情况下，用横截面超声心动图分析短轴面积或直径非常适合左心室容积的定量。
