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血红蛋白和血细胞比容:它们在检测贫血方面的敏感性相同吗?

Hemoglobins and hematocrits: are they equally sensitive in detecting anemias?

作者信息

Graitcer P L, Goldsby J B, Nichaman M Z

出版信息

Am J Clin Nutr. 1981 Jan;34(1):61-4. doi: 10.1093/ajcn/34.1.61.

DOI:10.1093/ajcn/34.1.61
PMID:7446459
Abstract

General medical and nutritional practice assumes that hemoglobin and hematocrit values are equally useful in detecting anemia and that they can be used interchangeably for anemia screening. These two tests, at presumed equivalent levels, identify varying prevalences of anemia in the same population. This study examines anemia prevalence rates using hemoglobin and hematocrit tests performed in seven separate surveys on a total of 13,040 children. These data indicate that hemoglobin and hematocrit screening tests are indeed not comparable in detecting anemia in the same population. Using only hematocrit tests, anemia is diagnosed in 1 to 10% of children with normal hemoglobin levels and is not detected in 20 to 50% of children who might be considered anemic on the basis of low hemoglobin levels.

摘要

一般医学和营养实践认为,血红蛋白和血细胞比容值在检测贫血方面同样有用,并且在贫血筛查中可以互换使用。这两项检测在假定的同等水平下,在同一人群中识别出不同的贫血患病率。本研究通过对总共13040名儿童进行的七项独立调查中所做的血红蛋白和血细胞比容检测来检查贫血患病率。这些数据表明,血红蛋白和血细胞比容筛查检测在同一人群中检测贫血时确实不可比。仅使用血细胞比容检测时,血红蛋白水平正常的儿童中有1%至10%被诊断为贫血,而根据低血红蛋白水平可能被视为贫血的儿童中有20%至50%未被检测出贫血。

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Prevalence of Plasmodium falciparum Parasitaemia and Its Correlation with Haematological Parameters among HIV-Positive Individuals in Nigeria.在尼日利亚,感染疟原虫恶性疟原虫的流行情况及其与 HIV 阳性个体血液学参数的相关性。
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3
Haemoglobin and haematocrit: the threefold conversion is also non valid for assessing anaemia in Plasmodium vivax malaria-endemic settings.
血红蛋白和血细胞比容:在间日疟原虫疟疾流行地区,三重转换对于评估贫血也无效。
Malar J. 2007 Dec 17;6:166. doi: 10.1186/1475-2875-6-166.
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Haemoglobin and haematocrit: is the threefold conversion valid for assessing anaemia in malaria-endemic settings?血红蛋白和血细胞比容:三重转换法在疟疾流行地区评估贫血时是否有效?
Malar J. 2007 May 22;6:67. doi: 10.1186/1475-2875-6-67.
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Accuracy of clinical pallor in the diagnosis of anaemia in children: a meta-analysis.临床面色苍白在儿童贫血诊断中的准确性:一项荟萃分析。
BMC Pediatr. 2005 Dec 8;5:46. doi: 10.1186/1471-2431-5-46.
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Status of nutrition surveillance activities in 24 State and metropolitan health departments.24个州和大城市卫生部门的营养监测活动状况。
Public Health Rep. 1983 Jul-Aug;98(4):349-55.