Meier G D, Bove A A, Santamore W P, Lynch P R
Am J Physiol. 1980 Dec;239(6):H794-804. doi: 10.1152/ajpheart.1980.239.6.H794.
Regional right ventricular (RV) motion was examined in six acutely instrumented dogs by implanting radiopaque markers in three regions of the free wall: the apex, the midventricle, and the outflow tract. These markers were filmed at the paced heart rate of 180 beats/min with a high-speed biplane X-ray system, and their motion was analyzed with a digital computer. Local deformation was separated into percent length changes in the two mutually perpendicular principal directions. The major component exhibited shortening along a path from apex to conus. (apex - 13.6%, midventricle -13.1%, conus -8.7%); the minor component exhibited small amounts of lengthening and some shortening (apex +4.7%, midventricle +1.8%, conus -0.5%). From these two measurements we calculated the peak RV free wall thickening (apex 13.6%, midventricle 14.1%, conus 10.9%). The experimental technique developed for this study was found to be suitable for the repeated analysis of intact ventricular performance in chronic animal studies. The results reveal that in systole the RV free wall undergoes a sequential contraction, which begins at the apex and ends in the conus.
通过在六只急性插管的犬的游离壁三个区域（心尖、心室中部和流出道）植入不透射线的标记物，对局部右心室（RV）运动进行了研究。使用高速双平面X射线系统以每分钟180次的起搏心率拍摄这些标记物，并通过数字计算机分析它们的运动。局部变形被分离为两个相互垂直的主方向上的长度变化百分比。主要成分表现为沿从心尖到圆锥的路径缩短（心尖 -13.6%，心室中部 -13.1%，圆锥 -8.7%）；次要成分表现为少量延长和一些缩短（心尖 +4.7%，心室中部 +1.8%，圆锥 -0.5%）。根据这两项测量，我们计算出右心室游离壁增厚峰值（心尖13.6%，心室中部14.1%，圆锥10.9%）。发现为本研究开发的实验技术适用于慢性动物研究中完整心室功能的重复分析。结果表明，在收缩期，右心室游离壁经历顺序性收缩，始于心尖，止于圆锥。
