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Synthetic nucleosides and nucleotides. XVI. Synthesis and biological evaluations of a series of 1-beta-D-arabinofuranosylcytosine 5'-alkyl or arylphosphates.

作者信息

Saneyoshi M, Morozumi M, Kodama K, Machida H, Kuninaka A, Yoshino H

出版信息

Chem Pharm Bull (Tokyo). 1980 Oct;28(10):2915-23. doi: 10.1248/cpb.28.2915.

DOI:10.1248/cpb.28.2915
PMID:7448940
Abstract
摘要

相似文献

1
Synthetic nucleosides and nucleotides. XVI. Synthesis and biological evaluations of a series of 1-beta-D-arabinofuranosylcytosine 5'-alkyl or arylphosphates.合成核苷与核苷酸。十六。一系列1-β-D-阿拉伯呋喃糖基胞嘧啶5'-烷基或芳基磷酸酯的合成与生物学评价。
Chem Pharm Bull (Tokyo). 1980 Oct;28(10):2915-23. doi: 10.1248/cpb.28.2915.
2
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The synthesis, characterization, and preliminary biological evaluation of 1-beta-D-arabinofuranosylcytosine-5'-diphosphate-L-1,2-dipalmitin.1-β-D-阿拉伯呋喃糖基胞嘧啶-5'-二磷酸-L-1,2-二棕榈酸酯的合成、表征及初步生物学评价
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Nucleic acids. 12. Synthesis of the L enantiomer of 1- -arabinofuranosylcytosine and of O 2 ,O 2' -anhydro-1- -D-arabinofuranosylcytosine.
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6
Evaluation of the conjugate between N4-(4-carboxybutyryl)-1-beta-D-arabinofuranosylcytosine and chitosan as a macromolecular prodrug of 1-beta-D-arabinofuranosylcytosine.N4-(4-羧基丁酰基)-1-β-D-阿拉伯呋喃糖基胞嘧啶与壳聚糖的缀合物作为1-β-D-阿拉伯呋喃糖基胞嘧啶的大分子前药的评价。
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Nucleoside conjugates. 14. Synthesis and antitumor activity of 1-beta-D-arabinofuranosylcytosine conjugates of ether lipids with improved water solubility.
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Nucleic acids. 11. Synthesis of 5'-esters of 1-beta-D-arabinofuranosylcytosine possessing antileukemic and immunosuppressive activity.核酸。11. 具有抗白血病和免疫抑制活性的1-β-D-阿拉伯呋喃糖基胞嘧啶5'-酯的合成。
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Synthesis of N-acetylglucosamine-modified ara-C and its effect on ovarian cancer cells.N-乙酰葡糖胺修饰的阿糖胞苷的合成及其对卵巢癌细胞的作用。
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Combined oral administration of etoposide and arabinofuranosylcytosine-5'-stearylphosphate enhances the antitumor effect against P388 ascites tumors.
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Deoxyribonucleoside triphosphate pools and Ara-CTP levels in P388 murine leukemic cells treated with 1-B-D-arabinofuranosylcytosine-5'-stearylphosphate which is a newly synthesized derivative of 1-B-D-arabinofuranosylcytosine.
Med Oncol Tumor Pharmacother. 1990;7(4):223-6. doi: 10.1007/BF02987099.