Suppr超能文献

[吸入麻醉下的脑结构单胺类物质]

[Brain structural monoamines under inhalation anesthesia].

作者信息

Girs E F, Zubriakov S V, Kopylov V N, Saliaev V N, Titov N S

出版信息

Farmakol Toksikol. 1980 May-Jun;43(3):280-4.

PMID:7449966
Abstract

It was established in albino rats that the activity of the processes that are responsible for the functioning of the metabolic link in noradrenaline synthesis varies under ether and ftorotan anesthesia. It was recorded that there is an increase in the activity of DOPA decarboxylation in the brain under deep ether anesthesia as well as in the activity of dopamine decarboxylation during egress from anesthesia. Ftorotan anesthesia is characterized by increased hydroxylation of phenylalanine and decarboxylation of DOPA, and by inhibition of the activity of tyrosine and dopamine hydroxylation. Egress of animals from ftorotan anesthesia is associated with an intensive noradrenaline formation in the brain.

摘要

在白化大鼠中已证实,负责去甲肾上腺素合成代谢环节功能的过程的活性,在乙醚和氟烷麻醉下会发生变化。据记录,深度乙醚麻醉时大脑中多巴脱羧酶的活性增加,以及麻醉苏醒过程中多巴胺脱羧酶的活性增加。氟烷麻醉的特征是苯丙氨酸羟化增加和多巴脱羧,以及酪氨酸和多巴胺羟化活性受到抑制。动物从氟烷麻醉中苏醒与大脑中去甲肾上腺素的大量生成有关。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验