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头孢呋辛:足月孕妇中的潜在应用。

Cefuroxime: potential use in pregnant women at term.

作者信息

Bousfield P, Browning A K, Mullinger B M, Elstein M

出版信息

Br J Obstet Gynaecol. 1981 Feb;88(2):146-9. doi: 10.1111/j.1471-0528.1981.tb00959.x.

DOI:10.1111/j.1471-0528.1981.tb00959.x
PMID:7459305
Abstract

The placental transfer of cefuroxime was studied in 20 women after one or more 1.5 g intravenous injections. Ten women had labour induced at term and ten were delivered by elective Caesarean section. High concentrations of cefuroxime were found in the cord blood and amniotic fluid and therapeutically active antibiotic levels were found in the infants for up to six hours after delivery.

摘要

在20名接受了一次或多次1.5克静脉注射头孢呋辛的女性中研究了其胎盘转运情况。10名女性足月引产,10名通过择期剖宫产分娩。在脐血和羊水中发现了高浓度的头孢呋辛,并且在分娩后长达6小时的婴儿体内发现了具有治疗活性的抗生素水平。

相似文献

1
Cefuroxime: potential use in pregnant women at term.头孢呋辛:足月孕妇中的潜在应用。
Br J Obstet Gynaecol. 1981 Feb;88(2):146-9. doi: 10.1111/j.1471-0528.1981.tb00959.x.
2
Placental transfer of cefuroxime.头孢呋辛的胎盘转运
Br J Obstet Gynaecol. 1981 Feb;88(2):141-5. doi: 10.1111/j.1471-0528.1981.tb00958.x.
3
Pharmacokinetics of cefuroxime in pregnancy.头孢呋辛在孕期的药代动力学
Am J Obstet Gynecol. 1982 Apr 1;142(7):823-8. doi: 10.1016/s0002-9378(16)32526-1.
4
[Cefuroxime: placental passage and concentrations in the uterus and adnexa uteri. Preliminary results].[头孢呋辛:胎盘转运及在子宫和子宫附件中的浓度。初步结果]
Ann Ostet Ginecol Med Perinat. 1980 Jul-Aug;101(4):235-43.
5
The placental transfer of cefuroxime at parturition.分娩时头孢呋辛的胎盘转运。
Eur J Obstet Gynecol Reprod Biol. 1994 May 18;54(3):177-80. doi: 10.1016/0028-2243(94)90278-x.
6
Cefuroxime prophylaxis in caesarean section.剖宫产术中头孢呋辛预防用药
Pharmatherapeutica. 1982;3(2):140-2.
7
The placental transfer of cimetidine.西咪替丁的胎盘转运。
Anaesthesia. 1981 Apr;36(4):371-5. doi: 10.1111/j.1365-2044.1981.tb10240.x.
8
Concentrations of ritodrine hydrochloride in maternal and fetal serum and amniotic fluid following intravenous administration in late pregnancy.妊娠晚期静脉注射后母体、胎儿血清及羊水内盐酸利托君的浓度
Eur J Obstet Gynecol Reprod Biol. 1986 Nov;23(3-4):145-52. doi: 10.1016/0028-2243(86)90142-5.
9
[Pharmacokinetics of cefuroxime in pregnant women with acute pyelonephritis].[头孢呋辛在急性肾盂肾炎孕妇中的药代动力学]
Antibiot Med Biotekhnol. 1985 Feb;30(2):124-8.
10
[Study of transplacental transmission of beta-lactam antibiotics (author's transl)].β-内酰胺类抗生素的胎盘转运研究(作者译)
J Gynecol Obstet Biol Reprod (Paris). 1979 Jun;8(4):359-64.

引用本文的文献

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Application of a Physiologically Based Pharmacokinetic Model to Predict Cefazolin and Cefuroxime Disposition in Obese Pregnant Women Undergoing Caesarean Section.应用基于生理的药代动力学模型预测剖宫产肥胖孕妇中头孢唑林和头孢呋辛的处置情况。
Pharmaceutics. 2022 May 30;14(6):1162. doi: 10.3390/pharmaceutics14061162.
2
Physiologically Based Pharmacokinetic Modeling of Renally Cleared Drugs in Pregnant Women.生理药代动力学模型在孕妇肾清除药物中的应用。
Clin Pharmacokinet. 2017 Dec;56(12):1525-1541. doi: 10.1007/s40262-017-0538-0.
3
Assessment of infant development during an 18-month follow-up after treatment of infections in pregnant women with cefuroxime axetil.
在使用头孢呋辛酯治疗孕妇感染后的18个月随访期间对婴儿发育进行评估。
Drug Saf. 2000 Jan;22(1):83-8. doi: 10.2165/00002018-200022010-00007.
4
Transplacental transfer of cefuroxime in uncomplicated pregnancies and those complicated by hydrops or changes in amniotic fluid volume.头孢呋辛在正常妊娠及合并水肿或羊水过少的妊娠中的胎盘转运情况。
Arch Dis Child. 1993 Jan;68(1 Spec No):54-7. doi: 10.1136/adc.68.1_spec_no.54.
5
Pharmacokinetics of cefuroxime in pregnant patients with preterm premature rupture of the membranes.头孢呋辛在胎膜早破的孕妇中的药代动力学。
Pharm Weekbl Sci. 1990 Dec 14;12(6A):275-9. doi: 10.1007/BF01967832.
6
Pharmacokinetics and tissue concentrations of cefuroxime.头孢呋辛的药代动力学和组织浓度
Pharm Weekbl Sci. 1990 Dec 14;12(6A):262-6; discussion 267. doi: 10.1007/BF01967830.