• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Plumbagin: A study of its anticancer, antibacterial & antifungal properties.

作者信息

Krishnaswamy M, Purushothaman K K

出版信息

Indian J Exp Biol. 1980 Aug;18(8):876-7.

PMID:7461745
Abstract
摘要

相似文献

1
Plumbagin: A study of its anticancer, antibacterial & antifungal properties.白花丹醌：对其抗癌、抗菌和抗真菌特性的研究。
Indian J Exp Biol. 1980 Aug;18(8):876-7.
2
Design, synthesis and biological evaluation of novel nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents.新型含氮和硫杂原子的1,4-萘醌作为高效抗真菌和抗菌剂的设计、合成及生物学评价
Eur J Med Chem. 2009 Aug;44(8):3130-7. doi: 10.1016/j.ejmech.2009.03.006. Epub 2009 Mar 21.
3
Synthesis and pharmacological studies of some 2-t-amino and 2,3-di-t-amino substituted 1,4-naphthoquinones and related compounds.一些2-叔氨基和2,3-二叔氨基取代的1,4-萘醌及其相关化合物的合成与药理学研究
Boll Chim Farm. 2002 Jul-Aug;141(4):304-10.
4
Synthesis and biological evaluation of novel (L)-alpha-amino acid methyl ester, heteroalkyl, and aryl substituted 1,4-naphthoquinone derivatives as antifungal and antibacterial agents.新型（L）-α-氨基酸甲酯、杂烷基和芳基取代的1,4-萘醌衍生物作为抗真菌和抗菌剂的合成及生物学评价
Bioorg Med Chem Lett. 2005 Dec 1;15(23):5324-8. doi: 10.1016/j.bmcl.2005.08.032. Epub 2005 Oct 3.
5
Approaches to new antibacterial and antiviral antibiotics.新型抗菌和抗病毒抗生素的研发方法。
Riv Biol. 1983 Summer;76(2):349-57.
6
[Experimental study of the antimicrobial properties and antineoplastic effect of the new pentaenic antibiotic 661].
Antibiotiki. 1969 Sep;14(9):849-52.
7
Synthesis and evaluation of antifungal activity of naphthoquinone derivatives.萘醌衍生物的合成及其抗真菌活性评价
Eur J Med Chem. 2006 Jun;41(6):773-8. doi: 10.1016/j.ejmech.2006.02.003. Epub 2006 Mar 24.
8
Antibacterial, antifungal and antitumoral activities of Micromycetes. I. Preliminary study.微真菌的抗菌、抗真菌和抗肿瘤活性。I. 初步研究。
Microbiologica. 1989 Oct;12(4):307-16.
9
Antimicrobial and antitumoral activities of 6-allyl-5,6-dihydro-5-hydroxypyran-2-one, a lactone produced by a new Drechslera species.一种由新德氏霉属物种产生的内酯——6-烯丙基-5,6-二氢-5-羟基吡喃-2-酮的抗菌和抗肿瘤活性
Pharmazie. 1994 Apr;49(4):279-81.
10
In vitro antifungal activity of extract and plumbagin from the stem bark of Diospyros crassiflora Hiern (Ebenaceae).粗柄柿（柿科）茎皮提取物及白花丹醌的体外抗真菌活性
Phytother Res. 2007 Jul;21(7):671-4. doi: 10.1002/ptr.2140.

引用本文的文献

1
Antibiofilm Activity of Sundew Species against Multidrug-Resistant Strains.猪毛菜属植物对多重耐药菌株的抗生物膜活性。
Int J Mol Sci. 2022 Nov 8;23(22):13720. doi: 10.3390/ijms232213720.
2
Plumbagin, a Natural Product with Potent Anticancer Activities, Binds to and Inhibits Dihydroorotase, a Key Enzyme in Pyrimidine Biosynthesis.白花丹素，一种具有强大抗癌活性的天然产物，与嘧啶生物合成中的关键酶二氢乳清酸酶结合并抑制其活性。
Int J Mol Sci. 2021 Jun 25;22(13):6861. doi: 10.3390/ijms22136861.
3
Potency, Safety, and Pharmacokinetic Profiles of Potential Inhibitors Targeting SARS-CoV-2 Main Protease.
靶向严重急性呼吸综合征冠状病毒2（SARS-CoV-2）主要蛋白酶的潜在抑制剂的效力、安全性和药代动力学特征
Front Pharmacol. 2021 Feb 1;11:630500. doi: 10.3389/fphar.2020.630500. eCollection 2020.
4
Phytochemical profile of (Thunb). Steud.（Thunb.）Steud.的植物化学特征
Phytochem Rev. 2015;14(5):799-833. doi: 10.1007/s11101-014-9376-y. Epub 2014 Aug 29.
5
Plumbagin shows anticancer activity in human osteosarcoma (MG-63) cells via the inhibition of S-Phase checkpoints and down-regulation of c-myc.白花丹醌通过抑制S期检查点和下调c-myc在人骨肉瘤（MG-63）细胞中显示出抗癌活性。
Int J Clin Exp Med. 2015 Aug 15;8(8):14432-9. eCollection 2015.
6
Antiproliferative effects of Plumbago rosea and its purified constituent plumbagin on SK-MEL 28 melanoma cell lines.玫瑰铅丹及其纯化成分白花丹醌对SK-MEL 28黑色素瘤细胞系的抗增殖作用。
Pharmacognosy Res. 2014 Oct;6(4):312-9. doi: 10.4103/0974-8490.138280.
7
Plumbagin reduces human colon cancer cell survival by inducing cell cycle arrest and mitochondria-mediated apoptosis.白花丹素通过诱导细胞周期停滞和线粒体介导的细胞凋亡来减少人结肠癌细胞的存活。
Int J Oncol. 2014 Nov;45(5):1913-20. doi: 10.3892/ijo.2014.2592. Epub 2014 Aug 8.
8
Anticancer compound plumbagin and its molecular targets: a structural insight into the inhibitory mechanisms using computational approaches.抗癌化合物白花丹醌及其分子靶点：基于计算方法对抑制机制的结构洞察
PLoS One. 2014 Feb 27;9(2):e87309. doi: 10.1371/journal.pone.0087309. eCollection 2014.
9
The cytotoxic effect of 2-acylated-1,4-naphthohydroquinones on leukemia/lymphoma cells.2-酰化-1,4-萘氢醌对白血病/淋巴瘤细胞的细胞毒性作用。
Bioorg Med Chem. 2014 Jan 15;22(2):842-7. doi: 10.1016/j.bmc.2013.12.007. Epub 2013 Dec 11.
10
Comparative study of three Plumbago L. species (Plumbaginaceae) by microscopy, UPLC-UV and HPTLC.三种白花丹属（蓝雪科）植物的显微镜、UPLC-UV 和 HPTLC 比较研究。
J Nat Med. 2013 Jul;67(3):554-61. doi: 10.1007/s11418-012-0717-0. Epub 2012 Nov 15.