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必需脂肪酸和前列腺素的作用。

The role of essential fatty acids and prostaglandins.

作者信息

Crawford M A

出版信息

Postgrad Med J. 1980 Aug;56(658):557-62. doi: 10.1136/pgmj.56.658.557.

Abstract

The FAO/WHO Rome Report recommended an increase in the consumption of fat in countries where malnutrition is endemic; for maintenance, 3% of the dietary energy as essential fatty acids (EFA) may be adequate; in pregnancy and lactation an additional 1.5 to 2.4% energy as EFA is needed. For population at high risk for atherosclerosis and coronary heart disease (CHD) the recommendations were to decrease saturated fat in particular and increase EFA intake in the diet, reduce sugar, alcohol and cholesterol. These recommendations were similar to those of the Royal College of Physicians but the report went further by saying that EFA loss through industrial hydrogenation should be minimized and associated nutrients such as vitamin E and carotene should be restored if lost in processing. In terms of production, they asked for an increase in edible plant oils in developing countries and requested that intensive animal feeding and breeding should be corrected to avoid the excess accumulation of saturated fats. In addition, the Rome Report requested meaningful labelling of amounts and quality of fat in foods containing added fats. The basic aims of the Report were to state the position of lipid nutrition. The issue of the nutrient correction in terms of CHD cannot properly be discussed without taking into account the essential components which are needed for the integrity and development of the vascular system.

摘要

粮农组织/世卫组织罗马报告建议,在营养不良普遍存在的国家增加脂肪摄入量;维持阶段,膳食能量的3%作为必需脂肪酸(EFA)可能就足够了;怀孕和哺乳期则需要额外摄入1.5%至2.4%能量的必需脂肪酸。对于动脉粥样硬化和冠心病(CHD)高危人群,建议尤其要减少饱和脂肪的摄入,增加膳食中必需脂肪酸的摄入量,减少糖、酒精和胆固醇的摄入。这些建议与皇家内科医师学院的建议相似,但该报告进一步指出,应尽量减少工业氢化过程中必需脂肪酸的损失,并且如果在加工过程中损失了维生素E和胡萝卜素等相关营养素,应予以补充。在生产方面,他们要求增加发展中国家食用植物油的产量,并要求纠正集约化动物饲养和繁殖方式,以避免饱和脂肪过度积累。此外,罗马报告要求对添加了脂肪的食品中脂肪的含量和质量进行有意义的标注。该报告的基本目标是阐明脂质营养的立场。如果不考虑血管系统完整性和发育所需的基本成分,就无法恰当地讨论冠心病方面的营养纠正问题。

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本文引用的文献

2
THE BIOSYNTHESIS OF PROSTAGLANDINS.前列腺素的生物合成
Biochim Biophys Acta. 1964 Jul 15;90:204-7. doi: 10.1016/0304-4165(64)90144-8.

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