[Changes in the surface charge of lipoproteins isolated from the plasma of persons with hyperalphalipoproteinemia].

In patients with hyperalphalipoproteinemia amount of positively charged groups was increased on the surface of high density lipoproteins and decreased on the surface of low density lipoproteins as shown by fluorescent probe with 1-aniline naphthalene 8-sulphonate. The alteration of the lipoprotein charges observed in blood plasma of the patients appears to serve as a protective mechanism against the heart ischemic disease in hyperalphalipoproteinemia.