Formaziuk V E, Dobretsov G E, Vladimirov Iu A
Vopr Med Khim. 1981 Jan-Feb;27(1):125-9.
In patients with hyperalphalipoproteinemia amount of positively charged groups was increased on the surface of high density lipoproteins and decreased on the surface of low density lipoproteins as shown by fluorescent probe with 1-aniline naphthalene 8-sulphonate. The alteration of the lipoprotein charges observed in blood plasma of the patients appears to serve as a protective mechanism against the heart ischemic disease in hyperalphalipoproteinemia.
用1-苯胺萘-8-磺酸盐荧光探针检测发现，高α脂蛋白血症患者体内，高密度脂蛋白表面带正电荷基团的数量增加，而低密度脂蛋白表面带正电荷基团的数量减少。患者血浆中观察到的脂蛋白电荷变化似乎是高α脂蛋白血症中预防心脏缺血性疾病的一种保护机制。
