Williams D R, Coller J A, Corman M L, Nugent F W, Veidenheimer M C
Dis Colon Rectum. 1981 Jan-Feb;24(1):22-4. doi: 10.1007/BF02603444.
Anal fissures, fistulas, and abscesses occurred as complications in 22 per cent of our population of 1,098 patients with Crohn's disease. Crohn's colitis was much more frequently associated with an anal lesion than Crohn's disease of the small bowel (52 per cent vs. 14 per cent). When an anal lesion is the manifesting sign, Crohn's disease will soon develop elsewhere in the intestine. Since these lesions frequently herald the onset of intestinal Crohn's disease, the physician must always be aware of the possibility of inflammatory bowel disease when dealing with suspicious anal lesions.
在我们1098例克罗恩病患者中，22%出现肛裂、肛瘘和脓肿等并发症。克罗恩病性结肠炎比小肠克罗恩病更常伴有肛门病变（52%对14%）。当肛门病变为首发症状时，克罗恩病很快会在肠道其他部位出现。由于这些病变常预示肠道克罗恩病的发作，医生在处理可疑肛门病变时必须始终意识到炎性肠病的可能性。
