Mizutani A, Taniguchi K, Miyagawa A, Ikebe H, Yoshitake S, Honda N
Department of Anesthesiology, Oita Medical University.
Masui. 1995 Aug;44(8):1076-9.
The analgesic effect of iontophoresis with magnesium sulfate was studied in fourteen healthy adult volunteers. Magnesium sulfate 0.5 mg.5 ml-1 was locally administered by the iontophoresis with 1.0 mA electric current for 10 min. The pain recognition time was measured by the pain thermometer before and after 5, 15, 30, 60 and 120 min of iontophoresis. The pain recognition time was significantly extended and lasted for 60 min. These results support the view that the iontophoresis with magnesium sulfate has analgesic effect and produces a good pain relief clinically.
在14名健康成年志愿者中研究了硫酸镁离子导入的镇痛效果。通过离子导入法以1.0 mA电流局部给予0.5 mg·5 ml⁻¹的硫酸镁，持续10分钟。在离子导入前以及导入后5、15、30、60和120分钟，使用疼痛温度计测量疼痛识别时间。疼痛识别时间显著延长并持续了60分钟。这些结果支持以下观点，即硫酸镁离子导入具有镇痛作用，并在临床上产生良好的疼痛缓解效果。
