Cabañes F J, Abarca M L, Bonavia R, Bragulat M R, Castellá G, Ferrer L
Faculty of Veterinary Medicine, Autonomous University of Barcelona, Spain.
Mycoses. 1995 Mar-Apr;38(3-4):131-3. doi: 10.1111/j.1439-0507.1995.tb00036.x.
A 5-year-old female Siamese cat was presented to the veterinary teaching hospital with a history of bronchopneumonia for 20 days. The cat had not responded to antibacterial chemotherapy and had developed a pronounced submandibular lymphadenopathy. Characteristically encapsulated yeast cells with narrow-necked buds were clearly seen in a fine-needle aspirate of the lymph node with an India ink preparation. Cryptococcus neoformans var. neoformans was identified. Susceptibility tests on the isolated strain were performed using antifungal tablets. The strain was sensitive to amphotericin B, fluconazole, itraconazole and ketoconazole and was resistant to 5-fluorocytosine. The cat was positive for feline immunodeficiency virus. Nevertheless, the cat was treated with ketoconazole for 3 months and apparently recovered. Three months later the animal was presented in a precomatose state. The owners refused to treat the animal and the cat was destroyed.
一只5岁的雌性暹罗猫因支气管肺炎病史20天被送至兽医教学医院。这只猫对抗菌化疗无反应，并出现了明显的下颌下淋巴结病。在淋巴结细针穿刺涂片并用印度墨汁染色的标本中清晰可见具有窄颈芽的典型包膜酵母细胞。鉴定为新型隐球菌新型变种。使用抗真菌片剂对分离菌株进行了药敏试验。该菌株对两性霉素B、氟康唑、伊曲康唑和酮康唑敏感，对5-氟胞嘧啶耐药。这只猫的猫免疫缺陷病毒检测呈阳性。尽管如此，这只猫用酮康唑治疗了3个月，明显康复。三个月后，这只动物呈昏迷前期状态。主人拒绝治疗这只动物，于是这只猫被安乐死了。
