Salas J, Tello V, Zavaleta A, Villegas L, Salas M, Fernández I, Vaisberg A
Depto. Académico de Ciencias Fisiológicas, Universidad Peruana Cayetano Heredia, Lima, Perú.
Rev Biol Trop. 1994 Apr-Aug;42(1-2):323-6.
The wound healing effects of Jathopha curcas latex upon surgical wound produced in Balb/c mice skin, were studied with a modification of the Hoowes-Sooy-Harvey method. The effects of topical treatment using single 50 ul doses of latex at different dilutions (10% to 100%) was compared with a multiple dose treatment (four 25 ul/dose q12h, latex 5% to 100%). The single dose treatment with 10%, 50% or 100% latex and the multiple dose treatment with dilutions between 5% and 10%, have a healing effect but only on males. The multiple dose treatment with 50% or pure undiluted latex produced caustic lesions to treated skin.
