Bresnahan K A, Howell J M, Wizorek J
Department of Emergency Medicine, Georgetown University, Washington, DC, USA.
Ann Emerg Med. 1995 Nov;26(5):575-8. doi: 10.1016/s0196-0644(95)70007-2.
To compare the tensile strength of lacerations closed with cyanoacrylate tissue adhesive, with suture, and with a combination of tissue adhesive and suture.
Randomized, controlled animal model study.
Animal care facility.
Sixteen albino guinea pigs.
Four incisions to deep fascia were created on the dorsum of each animal. Lacerations were closed with either tissue adhesive alone, tissue adhesive with subcutaneous suture, percutaneous suture alone, or percutaneous suture with subcutaneous suture. After 4 days, the breaking strengths of all wound closures were measured.
Wound closures made with cyanoacrylate tissue adhesive alone exhibited significantly less tensile strength at 4 days than closures made by the other three methods. Wound closures made with combined percutaneous and subcutaneous sutures were significantly stronger than all other groups.
Wound closures made with cyanoacrylate tissue adhesive alone have less tensile strength at 4 days than those made with tissue adhesive and subcutaneous suture or those closed by traditional suture methods.
比较使用氰基丙烯酸酯组织粘合剂、缝线以及组织粘合剂与缝线联合使用来闭合撕裂伤后的抗张强度。
随机对照动物模型研究。
动物护理设施。
16只白化豚鼠。
在每只动物的背部制造四个深至深筋膜的切口。撕裂伤分别单独用组织粘合剂、组织粘合剂加皮下缝线、单纯经皮缝线或经皮缝线加皮下缝线进行闭合。4天后，测量所有伤口闭合处的断裂强度。
仅使用氰基丙烯酸酯组织粘合剂进行的伤口闭合在4天时的抗张强度明显低于其他三种方法进行的闭合。经皮和皮下联合缝线进行的伤口闭合明显比所有其他组更强。
仅使用氰基丙烯酸酯组织粘合剂进行的伤口闭合在4天时的抗张强度低于使用组织粘合剂和皮下缝线或通过传统缝合方法闭合的伤口。
