Noordzij J P, Foresman P A, Rodeheaver G T, Quinn J V, Edlich R F
Department of Plastic Surgery, University of Virginia School of Medicine, Charlottesville 22908.
J Emerg Med. 1994 Sep-Oct;12(5):645-9. doi: 10.1016/0736-4679(94)90417-0.
The purpose of this experimental study was to compare the effect of a tissue adhesive, N-butyl-2-cyanoacrylate, on the wound's ability to resist infection and gain strength to the effect of percutaneous polypropylene suture. Percutaneous sutures damaged host defenses, inviting the growth of bacteria to a level that was significantly greater than that encountered with the tissue adhesive. Immediately after wound closure, percutaneous sutures provided a more secure closure, as measured by breaking strength, than did tissue adhesives. Seven days later, the breaking strengths of wounds closed by tissue adhesives did not differ significantly from those repaired with percutaneous sutures. Tissue adhesive closure requires less psychomotor skills than suture closure and is accomplished more rapidly than suture closure.
本实验研究的目的是比较组织黏合剂N-丁基-2-氰基丙烯酸酯对伤口抗感染能力和增强强度的效果与经皮聚丙烯缝线的效果。经皮缝线会损害宿主防御机制，使细菌生长水平显著高于组织黏合剂的情况。伤口闭合后立即测量，经皮缝线在断裂强度方面比组织黏合剂提供了更牢固的闭合。七天后，用组织黏合剂闭合的伤口的断裂强度与用经皮缝线修复的伤口的断裂强度没有显著差异。与缝线闭合相比，组织黏合剂闭合所需的心理运动技能更少，且完成速度更快。
