Williamson M E, Lewis W G, Miller A S, Sagar P M, Holdsworth P J, Johnston D
Academic Unit of Surgery, General Infirmary, Leeds, UK.
Br J Surg. 1995 Oct;82(10):1391-4. doi: 10.1002/bjs.1800821032.
Fifty patients had a restorative proctocolectomy with stapled end-to-end ileoanal anastomosis by the eversion technique. Median (interquartile range) maximum resting anal pressure was 90 (73-116) cmH2O before restorative proctocolectomy and 71 (51-88) cmH2O 1 year after surgery (P < 0.001). Median maximum squeeze pressure was 141 (110-185) cmH2O before surgery and 146 (118-186) cmH2O 1 year after surgery (P not significant). Median thresholds for sensation in the lower third of the anal canal before and 1 year after surgery were 5.3 and 7.1 mA, respectively (P = 0.006). One year after restorative proctocolectomy, all patients were continent, although two experienced leakage of mucus requiring a pad. Forty-two patients (84 per cent) could discriminate between faeces and flatus. Eversion of the anorectum during restorative proctocolectomy impairs the motor and sensory functions of the anal sphincter. Most patients achieved satisfactory anal continence, however, despite these physiological changes.
50例患者采用外翻技术行吻合器端端回肠肛管吻合术进行结直肠切除重建术。重建性结直肠切除术前,最大静息肛管压力中位数(四分位间距)为90(73 - 116)cmH₂O,术后1年为71(51 - 88)cmH₂O(P < 0.001)。最大收缩压力中位数术前为141(110 - 185)cmH₂O,术后1年为146(118 - 186)cmH₂O(P无统计学意义)。肛管下1/3感觉阈值术前和术后1年中位数分别为5.3和7.1 mA(P = 0.006)。重建性结直肠切除术后1年,所有患者均能保持大便节制,尽管有2例出现黏液渗漏需要使用护垫。42例患者(84%)能够区分粪便和气体。重建性结直肠切除术中直肠肛管外翻会损害肛门括约肌的运动和感觉功能。然而,尽管有这些生理变化,大多数患者仍能获得满意的肛门节制。