Stanisz A M
Department of Pathology, McMaster University, Hamilton, Canada.
Neuroimmunomodulation. 1994 Jul-Aug;1(4):217-30. doi: 10.1159/000097169.
In this minireview we will discuss some evidence suggesting that the immune response is under neuronal regulation. In particular, we will concentrate on the effects that various neuropeptides have on immunity both in vitro and in vivo. Of these, vasoactive intestinal peptide, substance P, somatostatin, and calcitonin gene related peptide will be discussed in detail. In addition, the effects of nerve growth factor on the immune system will be presented. Finally, a possible role for these neuropeptides in various diseases and its clinical relevance will be suggested.
在这篇微型综述中，我们将讨论一些证据，这些证据表明免疫反应受神经调节。特别是，我们将专注于各种神经肽在体外和体内对免疫的影响。其中，血管活性肠肽、P物质、生长抑素和降钙素基因相关肽将进行详细讨论。此外，还将介绍神经生长因子对免疫系统的影响。最后，将提出这些神经肽在各种疾病中的可能作用及其临床相关性。
