Oishi M, Mochizuki Y, Du C, Takasu T
Department of Neurology, Nihon University School of Medicine, Tokyo, Japan.
Electroencephalogr Clin Neurophysiol. 1995 Nov;95(5):346-9. doi: 10.1016/0013-4694(95)00084-c.
The contingent negative variation (CNV) and movement-related cortical potentials (MRCPs) were recorded in 10 cases of Parkinson's disease, 10 cases of vascular parkinsonism and 10 age-matched healthy controls. The amplitude of the early CNV was smaller in the Parkinson's disease group and the vascular parkinsonism group than in the healthy control group. The latencies of Bereitschaftspotential (BP) and negative slope (NS') were longer and the amplitude of BP was smaller in the Parkinson's disease group and the vascular parkinsonism group than in the healthy control group. These abnormalities in CNV and MRCPs were improved by intravenous injection of L-DOPA.
对10例帕金森病患者、10例血管性帕金森综合征患者及10例年龄匹配的健康对照者记录了伴随负变化（CNV）和运动相关皮质电位（MRCP）。帕金森病组和血管性帕金森综合征组早期CNV的波幅均低于健康对照组。帕金森病组和血管性帕金森综合征组的运动准备电位（BP）潜伏期和负向斜率（NS'）均延长，且BP波幅低于健康对照组。静脉注射左旋多巴可改善CNV和MRCP的这些异常。
